Suppr超能文献

Suprathel与Jelonet伤口敷料在酶促清创后烧伤创面愈合中的比较临床研究

Comparative Clinical Study of Suprathel and Jelonet Wound Dressings in Burn Wound Healing after Enzymatic Debridement.

作者信息

Heitzmann Wolfram, Mossing Mitja, Fuchs Paul Christian, Akkan Jan, Seyhan Harun, Grieb Gerrit, Opländer Christian, Schiefer Jennifer Lynn

机构信息

Clinic of Plastic, Reconstructive, Hand and Burn Surgery, Cologne-Merheim Hospital, Witten/Herdecke University, 51109 Cologne, Germany.

Department of Plastic Surgery and Hand Surgery, Gemeinschaftskrankenhaus Havelhoehe, Teaching Hospital of the Charité Berlin, Kladower Damm 221, 14089 Berlin, Germany.

出版信息

Biomedicines. 2023 Sep 22;11(10):2593. doi: 10.3390/biomedicines11102593.

Abstract

Following the enzymatic debridement of deep dermal burns, the choice of wound dressing is crucial for providing an adequate environment and suitable conditions for rapid wound healing. As Suprathel and fatty gauze (Jelonet) are the most commonly used dressings in burn centers, the aim of this study is to compare Suprathel and Jelonet in the treatment of deep dermal burns after enzymatic debridement with respect to wound healing, patient comfort, and pain. A total of 23 patients with deep dermal burns of the hand or foot (mean total body surface area of 4.31%) were included in this prospective, unicentric, open, comparative, and intra-individual clinical study. After enzymatic debridement, wounds were divided into two areas: one was treated with Suprathel and the other with Jelonet. Suprathel remained on the wounds without dressing changes while Jelonet was regularly changed. Wound healing, infection, bleeding, exudation, time for dressing changes, and pain were documented (from days 2 to 48) after injury. Satisfactory results were obtained in 22 cases; only one patient had to undergo a second debridement followed by skin grafting. No significant difference in time to final wound healing could be observed (18-19 d). Patients reported significantly less pain during the dressing changes for Suprathel compared to Jelonet. Furthermore, the wound areas treated with Suprathel showed significantly less exudation and bleeding. Wound infections rarely occurred in both groups. In conclusion, the authors found that both wound dressings could be used to achieve safe and rapid wound healing after the enzymatic debridement of deep dermal burns of the hands and feet. However, compared to Jelonet, Suprathel showed superior results in terms of patient comfort and pain reduction.

摘要

在对深度真皮烧伤进行酶促清创后,伤口敷料的选择对于为伤口快速愈合提供适宜环境和条件至关重要。由于Suprathel和脂肪纱布(Jelonet)是烧伤中心最常用的敷料,本研究旨在比较Suprathel和Jelonet在酶促清创后治疗深度真皮烧伤时在伤口愈合、患者舒适度和疼痛方面的差异。本前瞻性、单中心、开放性、对比性和个体内临床研究共纳入23例手部或足部深度真皮烧伤患者(平均总体表面积为4.31%)。酶促清创后,伤口分为两个区域:一个区域用Suprathel治疗,另一个区域用Jelonet治疗。Suprathel留在伤口上,无需更换敷料,而Jelonet则定期更换。记录受伤后(第2天至48天)的伤口愈合、感染、出血、渗出、换药时间和疼痛情况。22例患者取得了满意的结果;只有1例患者不得不再次进行清创,随后进行植皮。最终伤口愈合时间无显著差异(18 - 19天)。与Jelonet相比,患者报告在更换Suprathel敷料时疼痛明显减轻。此外,用Suprathel治疗的伤口区域渗出和出血明显较少。两组伤口感染均很少发生。总之,作者发现两种伤口敷料均可用于在对手部和足部深度真皮烧伤进行酶促清创后实现安全快速的伤口愈合。然而,与Jelonet相比,Suprathel在患者舒适度和减轻疼痛方面显示出更好的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cd4/10603925/9c78f4b04e3f/biomedicines-11-02593-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验