Bains Aarti, Najda Agnieszka, Chawla Prince, Klepacka Joanna, Dhull Sanju Bala, Sadh Pardeep Kumar, Khan Mohammed Azhar, Kaushik Ravinder
Department of Biotechnology, CT Institute of Pharmaceutical Sciences, South Campus, Jalandhar 144020, Punjab, India.
School of Biotechnology, Shoolini University, Solan 173229, Himachal Pradesh, India.
Polymers (Basel). 2022 May 10;14(10):1938. doi: 10.3390/polym14101938.
Interest in the utilization of plant-based bioactive compounds in foods has increased due to their biochemical activities and as alternatives in the reduction of high concentrations of chemical utilization. However, some of these additives are hydrophobic, thus being harder to disperse into the hydrophilic food matrix. Therefore, an oil-in-water nanoemulsion (RRE1-RRE10) was formulated with different concentrations of red rice extract (1-10% /). Nanoemulsion showed droplet sizes within the range of 157.33-229.71 nm and the best formulation (RRE5) was selected based on the creaming index which was stable to flocculation over a range of temperatures (30-90 °C), pH (2-9), and salt concentration (100-600 mM). It showed significantly improved antioxidant and anti-inflammatory activity as compared to its other counterparts. Potential antimicrobial activity against was attributed to RRE5 nanoemulsion as compared to . Therefore, due to the potential bioactivity of RRE5 nanoemulsion, it can be scaled up at the industrial level.
由于植物源生物活性化合物的生化活性以及它们作为减少高浓度化学物质使用替代品的作用,人们对其在食品中的应用兴趣日益增加。然而,其中一些添加剂具有疏水性,因此更难分散到亲水性食品基质中。因此,制备了不同浓度(1%-10%)红米提取物的水包油纳米乳液(RRE1-RRE10)。纳米乳液的液滴尺寸在157.33-229.71纳米范围内,并根据在一系列温度(30-90°C)、pH值(2-9)和盐浓度(100-600 mM)下对絮凝稳定的乳析指数选择了最佳配方(RRE5)。与其他配方相比,它表现出显著提高的抗氧化和抗炎活性。与[对比物]相比,RRE5纳米乳液对[目标微生物]具有潜在的抗菌活性。因此,由于RRE5纳米乳液的潜在生物活性,它可以在工业规模上进行扩大生产。