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新型双管内镜治疗退行性腰椎管狭窄症老年患者的临床疗效和生活质量。

Clinical Outcomes and Quality of Life in Elderly Patients Treated with a Newly Designed Double Tube Endoscopy for Degenerative Lumbar Spinal Stenosis.

机构信息

Department of Spinal Surgery, Qingdao Municipal Hospital, Qingdao, China.

Department of Spinal Surgery, The People's Hospital of Dianjiang Country, Chongqing, China.

出版信息

Orthop Surg. 2022 Jul;14(7):1359-1368. doi: 10.1111/os.13304. Epub 2022 May 27.

Abstract

OBJECTIVE

To evaluate the clinical outcome and quality of life in elderly patients in poor conditions with unilateral symptomatic degenerative lumbar spinal stenosis (DLSS) who were treated with percutaneous endoscopic lumbar discectomy (PELD) assisted by double tubes.

METHODS

This study was designed retrospectively. From June 2017 to June 2018, 31 consecutive elderly patients who were presented with unilateral symptomatic DLSS, underwent PELD assisted by double tubes under local anesthesia. American Society of Anesthesiology score (ASA) was used to evaluate the patients' conditions. The operative time, intraoperative blood loss, hospital stay, and complications were evaluated. Clinical outcomes were assessed by the visual analog scale (VAS), Oswestry disability index (ODI), and modified Macnab criteria. Short Form 36 (SF-36) was used to evaluate the life quality. The CT or MRI was used to evaluate the spinal area.

RESULTS

Thirty-one patients were enrolled and 25 cases achieved at least a 24-month follow-up. Three patients were lost to follow-up and three patients died from other diseases. A total of 76% (19/25) of the patients presented an ASA score of more than 3. The mean operative time was 67.80 min, the mean blood loss was 18.2 ml, and the hospital stay was 6.92 days. The postoperative 12-month follow-up VAS score significantly decreased compared with that before the operation (1.12 ± 0.73 vs. 5.12 ± 1.81, p < 0.01). Although the VAS score decreased at the final follow-up, there was no significant difference compared with that at the 12-month follow-up (0.92 ± 0.64 vs. 1.12 ± 0.73, p = 0.549). So did the ODI. Also, there was no difference in the ODI scores between the 12-month follow-up and the final follow-up (12.52 ± 5.58 vs. 9.44 ± 6.32, p = 0.172). The overall excellent rate was 92% (23/25) at the final follow-up. The scores of the physical function, mental function, and social function of SF-36 after the operation improved significantly compared with those before operation (p < 0.05). But there was no difference in the physical function score (84.00 ± 6.29 vs 84.40 ± 6.18, p = 0.871), mental function score (81.76 ± 8.01 vs 81.68 ± 6.67, p = 0.974), or social function score (115.50 ± 13.64 vs 118.50 ± 12.03, p = 0.437) between the 12-month follow-up and the final follow-up. There were no differences in the VAS, ODI, and SF-36 between the L and L S groups before operation or at the final follow-up (p > 0.05). The postoperative radiology indicated the lateral recess is opened and the area of the dural sac is expanded. Two cases (8.0%, 2/25) experienced recurrence and a secondary PELD was performed.

CONCLUSIONS

PELD assisted by double tubes is effective for unilateral symptomatic DLSS in elderly patients with comorbidities and could improve life quality.

摘要

目的

评估采用双管辅助经皮内窥镜腰椎间盘切除术(PELD)治疗合并症的单侧症状性退变性腰椎管狭窄症(DLSS)老年患者的临床疗效和生活质量。

方法

本研究为回顾性研究。2017 年 6 月至 2018 年 6 月,31 例单侧症状性 DLSS 老年患者在局部麻醉下接受双管辅助 PELD 治疗。美国麻醉医师协会(ASA)评分用于评估患者病情。评估手术时间、术中出血量、住院时间和并发症。采用视觉模拟评分(VAS)、Oswestry 功能障碍指数(ODI)和改良 Macnab 标准评估临床疗效。采用简明健康状况调查表 36 项(SF-36)评估生活质量。采用 CT 或 MRI 评估脊柱区域。

结果

共纳入 31 例患者,25 例获得至少 24 个月随访。3 例失访,3 例因其他疾病死亡。共有 76%(19/25)的患者 ASA 评分>3 分。平均手术时间为 67.80 min,平均出血量为 18.2 ml,住院时间为 6.92 d。术后 12 个月随访 VAS 评分较术前明显降低(1.12±0.73 vs. 5.12±1.81,p<0.01)。尽管终末随访时 VAS 评分较 12 个月随访时有所下降,但两者之间无显著差异(0.92±0.64 vs. 1.12±0.73,p=0.549)。ODI 评分也如此。12 个月随访和终末随访时 ODI 评分无差异(12.52±5.58 vs. 9.44±6.32,p=0.172)。终末随访时总体优良率为 92%(23/25)。术后 SF-36 量表的生理功能、心理功能和社会功能评分较术前显著提高(p<0.05)。但生理功能评分(84.00±6.29 vs 84.40±6.18,p=0.871)、心理功能评分(81.76±8.01 vs 81.68±6.67,p=0.974)和社会功能评分(115.50±13.64 vs 118.50±12.03,p=0.437)在 12 个月随访和终末随访时无差异。术前和终末随访时,L 组和 L S 组的 VAS、ODI 和 SF-36 评分均无差异(p>0.05)。术后影像学提示侧隐窝开放,硬脊膜囊面积扩大。2 例(8.0%,2/25)复发,再次行 PELD 治疗。

结论

双管辅助 PELD 治疗合并症的单侧症状性 DLSS 老年患者有效,可提高生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d1e/9251268/405a05d2d56f/OS-14-1359-g004.jpg

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