Almond N M, Parkhouse R M, Chapa-Ruiz M R, Garcia-Ortigoza E
Trop Med Parasitol. 1986 Dec;37(4):381-4.
Biochemically characterised surface and secreted stage specific antigens were used to analyse the response of humans to infection with Trichinella spiralis. Immuno-coprecipitation and SDS-PAGE of labelled proteins were used to dissect the humoral response of Mexican and European infected sera to each component antigen. The results demonstrate that in man, like laboratory rodents, the response to each protein varies independently. In addition, they permit a more rational approach to the development of improved immuno-diagnostic techniques.
利用经过生物化学特征鉴定的表面和分泌阶段特异性抗原，分析人类对旋毛虫感染的反应。采用标记蛋白的免疫共沉淀和SDS - PAGE技术，剖析墨西哥和欧洲感染血清对每种成分抗原的体液免疫反应。结果表明，在人类中，如同实验啮齿动物一样，对每种蛋白质的反应是独立变化的。此外，这些结果为开发改进的免疫诊断技术提供了更合理的方法。
