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就诊于三级医疗中心皮肤科的睑黄瘤患者的血脂异常:一项描述性横断面研究。

Dyslipidemia in Patients with Xanthelasma Palpebrarum Visiting the Department of Dermatology of a Tertiary Care Centre: A Descriptive Cross-sectional Study.

机构信息

Department of Dermatology, Nobel Medical College and Teaching Hospital, Kanchanbari, Biratnagar, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2022 Jun 1;60(250):529-532. doi: 10.31729/jnma.7485.

Abstract

INTRODUCTION

Xanthelasma palpebrarum refers to lipid deposition that occurs on eyelids and inner canthi. It is an important cutaneous manifestation of hyperlipidemia, atherosclerosis and coronary artery disease. Few studies have been done in Nepal regarding lipid abnormality in xanthelasma patients. The aim of this study was to find out the prevalence of dyslipidemia among patients with xanthelasma palpebrarum visiting the Department of Dermatology of a tertiary care centre.

METHODS

This is a descriptive cross-sectional study conducted among 80 patients from January, 2021 to February, 2022 in the Department of Dermatology of a tertiary care centre. Ethical approval was taken from the Institutional Review Committee (Reference number: 60512021). Convenience sampling was used. Lipid profile analysis was done among patients with clinical diagnosis of xanthelasma palpabrarum. Data was collected using Microsoft Excel for Mac version 16.16.27 and analyzed using the Statistical Package for the Social Sciences version 22.0. Point estimate at 90% Confidence Interval was calculated along with frequency and proportion for binary data.

RESULTS

Out of 80 patients with xanthelasma palpebrarum, the prevalence of dyslipidemia was 64 (80.00%) (74-86 at 90% Confidence Interval). Among them, 29 (45.31%) were males and 35 (54.69%) were females.

CONCLUSIONS

In our study, the prevalence of dyslipidemia among patients with xanthelasma palpebrarum was found to be higher than in similar studies conducted in similar settings.

KEYWORDS

dyslipidemia; gender; lipid.

摘要

引言

睑黄瘤是指发生于眼睑及内眦处的脂质沉积,是高血脂、动脉粥样硬化和冠心病的重要皮肤表现。尼泊尔对睑黄瘤患者脂质异常的研究较少。本研究旨在探讨在一家三级保健中心皮肤科就诊的睑黄瘤患者中血脂异常的患病率。

方法

这是一项在 2021 年 1 月至 2022 年 2 月期间在一家三级保健中心皮肤科进行的描述性横断面研究。本研究已获得机构审查委员会的伦理批准(参考编号:60512021)。采用便利抽样法。对临床诊断为睑黄瘤的患者进行血脂谱分析。使用 Microsoft Excel for Mac 版本 16.16.27 收集数据,并使用统计软件包 22.0 进行分析。计算了 90%置信区间的点估计值以及二项数据的频率和比例。

结果

在 80 例睑黄瘤患者中,血脂异常的患病率为 64 例(80.00%)(90%置信区间为 74-86)。其中,男性 29 例(45.31%),女性 35 例(54.69%)。

结论

在我们的研究中,发现睑黄瘤患者血脂异常的患病率高于在类似环境下进行的类似研究。

关键词

血脂异常;性别;脂质。

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The pathogenesis and clinical significance of xanthelasma palpebrarum.睑黄瘤的发病机制及临床意义。
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本文引用的文献

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Xanthelasma palpebrarum - a brief review.睑黄瘤——简要综述。
Clin Cosmet Investig Dermatol. 2017 Dec 18;11:1-5. doi: 10.2147/CCID.S130116. eCollection 2018.
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Diffuse "essential" normolipemic xanthomatosis.弥漫性“原发性”血脂正常性黄瘤病
Int J Dermatol. 1975 Nov;14(9):651-6. doi: 10.1111/j.1365-4362.1975.tb00157.x.

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