Department of Internal Medicine, Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, Nepal.
Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2021 Dec 11;59(244):1225-1228. doi: 10.31729/jnma.7152.
Hyponatremia is a frequent problem in chronic liver disease. To the best of our knowledge, no study of hyponatremia in chronic liver disease has been conducted in our setting. The aim of this study is to study the prevalence of hyponatremia in patients with chronic liver disease attending the outpatient department of a tertiary care hospital.
This descriptive cross-sectional study was conducted in 114 patients with chronic liver disease attending the out-patient department of a tertiary care hospital in Kathmandu, Nepal between November 2020 and July 2021. Ethical approval was taken from the Institutional Review Committee of Nepal Medical College and Teaching Hospital (Reference number: 028-077/078). Convenience sampling was done. The collected data was entered and analyzed in Microsoft Excel. Calculation of point estimate at 95% confidence interval was done along with frequency and proportion for binary data.
Among 114 patients with chronic liver disease studied, 47 (41.22%) (32.18-50.25 at 95% Confidence Interval) patients had hyponatremia (≤130mmol/L) with mean age of 53.44±7.57 years. Thirty (63.8%) patients out of these were males and 17 (36.2%) patients were females.
The prevalence of hyponatremia among patients with chronic liver disease was found to be higher when compared to other similar studies.
低钠血症是慢性肝脏疾病中的常见问题。据我们所知，在我们的研究环境中，尚未对慢性肝脏疾病中的低钠血症进行研究。本研究旨在研究在尼泊尔加德满都一家三级保健医院的门诊就诊的慢性肝脏疾病患者中低钠血症的患病率。
这是一项在尼泊尔医学学院和教学医院机构审查委员会（编号：028-077/078）批准下，于 2020 年 11 月至 2021 年 7 月期间，在尼泊尔加德满都一家三级保健医院的门诊就诊的 114 例慢性肝脏疾病患者中进行的描述性横断面研究。采用便利抽样法。收集的数据输入并在 Microsoft Excel 中进行分析。在 95%置信区间内计算点估计值，同时对二进制数据进行频率和比例计算。
在 114 例慢性肝脏疾病患者中，47 例（41.22%）（95%置信区间为 32.18-50.25）患者患有低钠血症（≤130mmol/L），平均年龄为 53.44±7.57 岁。其中 30 例（63.8%）患者为男性，17 例（36.2%）患者为女性。
与其他类似研究相比，慢性肝脏疾病患者的低钠血症患病率较高。
