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80 岁以上患者行钬激光前列腺剜除术的疗效。

Outcomes of octogenarians undergoing holmium laser enucleation of prostate.

机构信息

Department of Urology, Indiana University School of Medicine, 535 Barnhill Drive, Suite 150, Indianapolis, IN, 46202, USA.

出版信息

World J Urol. 2022 Jul;40(7):1751-1754. doi: 10.1007/s00345-022-04053-9. Epub 2022 May 28.

Abstract

PURPOSE

Holmium laser enucleation of prostate (HoLEP) is an effective surgical procedure in men with BPH. Due to the increase in the use of medical therapy for BPH related lower urinary symptoms more octogenarians are presenting in a delayed fashion with significant symptoms and urinary retention. We evaluate the feasibility and safety of octogenarians undergoing HoLEP.

METHODS

We performed a retrospective review of HoLEPs at our institution from July 2018 to December 2019. Patients were stratified into two groups based on age: < 80 and ≥ 80.

RESULTS

A total of 458 patients were identified, with 74 (16.2%) ≥ 80. In patients ≥ 80, prostate volume was higher (p < 0.0005), there was a higher rate of antiplatelet/anticoagulation (p = 0.029) use, and a lower rate of alpha-blocker use (p = 0.0016). As expected, ASA scores which correlate with increasing number of concomitant diseases were greater in the ≥ 80 cohort (p = 0.016). There was no significant difference in intraoperative complications (p = 0.14), 90 day complication (p = 0.34), readmission rates (p = 0.425) or emergency room visits between groups (p = 0.15).

CONCLUSIONS

Despite higher medical comorbidities and increased rates of anticoagulation in octogenarians, there is no increase in operative or postoperative complication rates. Age alone should not be used as exclusion criteria for HoLEP.

摘要

目的

钬激光前列腺剜除术(HoLEP)是治疗 BPH 的有效手术方法。由于 BPH 相关下尿路症状的药物治疗增加,更多的 80 岁以上老年人出现明显症状和尿潴留,就诊时间延迟。我们评估 80 岁以上老年人行 HoLEP 的可行性和安全性。

方法

我们对我院 2018 年 7 月至 2019 年 12 月期间行 HoLEP 的患者进行回顾性分析。根据年龄将患者分为两组:<80 岁和≥80 岁。

结果

共纳入 458 例患者,其中 74 例(16.2%)≥80 岁。在≥80 岁的患者中,前列腺体积更大(p<0.0005),抗血小板/抗凝药物使用比例更高(p=0.029),α受体阻滞剂使用比例更低(p=0.0016)。与合并症数量增加相关的 ASA 评分在≥80 岁组更高(p=0.016)。两组之间术中并发症(p=0.14)、90 天并发症(p=0.34)、再入院率(p=0.425)或急诊就诊率(p=0.15)无显著差异。

结论

尽管 80 岁以上老年人合并症更多,抗凝治疗比例更高,但手术或术后并发症发生率并未增加。年龄本身不应作为 HoLEP 的排除标准。

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