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基底细胞癌的管理:临床经验

Management of Basal Cell Carcinomas: Clinical Experience.

作者信息

Kara İrfan, Vural Alperen, Ünlü Metin, Şan Furkan, Benan Göçer Gülten, Yıldız Muhammed Gazi

机构信息

Department of Otorhinolaryngology, Kahramanmaraş Sütçü İmam University School of Medicine, Kahramanmaraş, Turkey.

Department of Otorhinolaryngology, Erciyes University School of Medicine, Kayseri, Turkey.

出版信息

Turk Arch Otorhinolaryngol. 2022 Mar;60(1):9-15. doi: 10.4274/tao.2022.2021-6-11. Epub 2022 May 12.

Abstract

OBJECTIVE

Basal cell carcinomas (BCC) mostly originate from the head and neck region. Main goal in BCC treatment is to achieve both aesthetic and functional results while observing the principles of tumor surgery. We report our experience regarding the clinical, histopathological features and surgical treatment results of head and neck basal cell carcinomas in the light of the literature.

METHODS

Files of patients with head and neck BCCs treated surgically in two university hospitals were retrospectively analyzed. Sociodemographic variables, location and size of tumor, pathological subtype, recurrence ratio, complications and technique of reconstruction were evaluated.

RESULTS

We analyzed 119 tumoral lesions in 105 patients of whom 55 (52.4%) were male and 50 (47.6%) were female. Their mean age was 67.3±12 years. The nasal region was the most common location area (n=42, 35.3%). Mean tumor size was 12.6 mm and tumor size range was 2-85 mm. The most commonly used reconstruction techniques were flap surgery, followed by primary closure, and skin grafts.

CONCLUSION

It is important to remove the tumor with a clear surgical margin at least 4 mm and evaluate the five surgical margins with frozen sections intraoperatively. Operations are often performed under local anesthesia and are well tolerated by patients. The most common flaps used in the reconstruction are not only easy to learn but also sufficient in most cases. Skin grafts are good choices in defects located in the cavum concha and the external meatus.

摘要

目的

基底细胞癌(BCC)大多起源于头颈部区域。BCC治疗的主要目标是在遵循肿瘤外科原则的同时实现美学和功能效果。我们根据文献报告我们关于头颈部基底细胞癌的临床、组织病理学特征及手术治疗结果的经验。

方法

对在两家大学医院接受手术治疗的头颈部BCC患者的病历进行回顾性分析。评估社会人口统计学变量、肿瘤的位置和大小、病理亚型、复发率、并发症及重建技术。

结果

我们分析了105例患者的119个肿瘤病灶,其中男性55例(52.4%),女性50例(47.6%)。他们的平均年龄为67.3±12岁。鼻区是最常见的发病部位(n = 42,35.3%)。肿瘤平均大小为12.6 mm,大小范围为2 - 85 mm。最常用的重建技术是皮瓣手术,其次是一期缝合和植皮。

结论

以至少4 mm的清晰手术切缘切除肿瘤并在术中用冰冻切片评估五个手术切缘很重要。手术通常在局部麻醉下进行,患者耐受性良好。重建中最常用的皮瓣不仅易于学习,而且在大多数情况下足够用。对于位于耳甲腔和外耳道的缺损,植皮是很好的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/592e/9103570/4b442440dcaf/tao-60-9-g1.jpg

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