严重急性呼吸综合征冠状病毒 2 感染的急性后期后遗症。
Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
机构信息
Division of Pulmonary, Allergy, and Critical Care Medicine, School of Medicine, Oregon Health & Science University (OHSU), 3181 SW Sam Jackson Park Road, Portland, Oregon, 97239, USA.
Department of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, 413 East 69th Street, Belfer Research Building, BB-512, New York, NY 10021, USA.
出版信息
Infect Dis Clin North Am. 2022 Jun;36(2):379-395. doi: 10.1016/j.idc.2022.02.004. Epub 2022 Feb 15.
Abstract
Postacute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or long coronavirus disease (COVID) is an emerging syndrome characterized by multiple persisting or newly emergent symptoms following the acute phase of SARS-CoV-2 infection. For affected patients, these prolonged symptoms can have a relapsing and remitting course and may be associated with disability and frequent health care utilization. Although many symptom-driven treatments are available, management remains challenging and often requires a multidisciplinary approach. This article summarizes the emerging consensus on definitions, epidemiology, and pathophysiology of long COVID and discusses what is understood about prevention, evaluation, and treatment of this syndrome.
摘要
严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）或长冠状病毒病（COVID）的急性后期是一种新出现的综合征，其特征是在 SARS-CoV-2 感染的急性期后出现多种持续存在或新出现的症状。对于受影响的患者，这些长期症状可能具有反复发作和缓解的过程，并且可能与残疾和频繁的医疗保健利用有关。尽管有许多针对症状的治疗方法，但管理仍然具有挑战性，通常需要多学科方法。本文总结了长 COVID 的定义、流行病学和病理生理学方面的新兴共识，并讨论了对这种综合征的预防、评估和治疗的理解。
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