Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.
Department of Neurological Surgery, University of Washington, Seattle, WA, USA.
Am J Surg. 2022 Oct;224(4):1150-1155. doi: 10.1016/j.amjsurg.2022.05.016. Epub 2022 May 25.
Estimation of long-term quality of life in patients sustaining Traumatic brain injuries is a difficult but important task during the early hospitalization. There are very limited tools to assess these outcomes, therefore we aimed to develop a predictive model for quality-of-life that could be used in hospitalized adults with TBIs.
The TRACK-TBI dataset was used to identify adult patients with TBI from 2014 to 2018. Multiple variables were assessed to predict favorable versus unfavorable scores on the Quality of Life after Brain Injury-Overall Scale (QOLIBRI-OS).
We included 1549 subjects. 57% had a favorable outcome, and were more likely to have private insurance, higher GCS scores, and fewer comorbidities. A model (TBI-PRO) for 3, 6, and 12-month QOLIBRI score was created. The AUROCs for predicting 3, 6 and 12-month favorable QOLIBRI scores were 0.81, 0.79, and 0.76, respectively.
The TBI-PRO model adequately estimates long-term outcomes in patients with TBI.
在患者住院期间，估计创伤性脑损伤患者的长期生活质量是一项困难但重要的任务。评估这些结果的工具非常有限，因此我们旨在开发一种可用于住院创伤性脑损伤患者的预测生活质量的模型。
使用 TRACK-TBI 数据集从 2014 年至 2018 年确定患有 TBI 的成年患者。评估了多个变量，以预测脑损伤后生活质量总体量表（QOLIBRI-OS）的有利与不利评分。
我们纳入了 1549 名患者。57%的患者预后良好，他们更有可能拥有私人保险、更高的 GCS 评分和更少的合并症。创建了一个用于预测 3、6 和 12 个月 QOLIBRI 评分的 TBI-PRO 模型。预测 3、6 和 12 个月有利 QOLIBRI 评分的 AUROC 分别为 0.81、0.79 和 0.76。
TBI-PRO 模型可充分评估 TBI 患者的长期预后。
