Younis Moataz, Adly Mohammed, Yousry Mohamed, Zahran Adel, Elmoheen Amr
Emergency Department, Hamad Medical Corporation, Doha, QAT.
Medicine, Qatar University, Doha, QAT.
Cureus. 2022 Apr 24;14(4):e24441. doi: 10.7759/cureus.24441. eCollection 2022 Apr.
Cerebrospinal Fluid (CSF) leakage results from a defect in the skull base, which communicates the subarachnoid space with the nasal cavity. The most common cause of CSF leakage is traumatic, and non-traumatic causes are less common. This case report illustrates a case of a woman who presented to the emergency department with clear fluid pouring from her nose for three weeks with a fever. The patient had pneumococcal meningitis and Idiopathic Intracranial Hypertension (ICH) seven years ago. Computed Tomography (CT) sinuses showed the defect seen on the right side of the cribriform plate, and the Magnetic Resonant Imaging (MRI) confirmed the CSF leakage. The CSF leakage was diagnosed by positive B transferrin. This case highlights a rare condition that needs early detection and treatment to prevent complications such as ascending meningitis.
脑脊液（CSF）漏是由颅底缺损引起的，该缺损使蛛网膜下腔与鼻腔相通。脑脊液漏最常见的原因是外伤，非外伤原因则较少见。本病例报告展示了一名女性患者的情况，她因鼻腔持续三周流出清亮液体并伴有发热而到急诊科就诊。该患者七年前曾患肺炎球菌性脑膜炎和特发性颅内高压（ICH）。鼻窦计算机断层扫描（CT）显示筛板右侧存在缺损，磁共振成像（MRI）证实了脑脊液漏。通过转铁蛋白B阳性确诊了脑脊液漏。本病例突出了一种罕见疾病，需要早期检测和治疗以预防诸如上行性脑膜炎等并发症。
