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精神分裂症患者的创伤后应激障碍:摩洛哥乌季达市精神科的一项横断面研究。

Post-traumatic stress disorder in patients treated for schizophrenia: A cross-sectional study in the psychiatric department of Oujda, Morocco.

作者信息

El Jabiry Salah-Eddine, Barrimi Mohamed, Oneib Bouchra, El Ghazouani Fatima

机构信息

Department of Psychiatry, Mohammed VI University Hospital of Oujda, Morocco.

Faculty of Medicine and Pharmacy, Mohammed the First University of Oujda, Morocco.

出版信息

Ann Med Surg (Lond). 2022 Apr 25;77:103651. doi: 10.1016/j.amsu.2022.103651. eCollection 2022 May.

Abstract

UNLABELLED

The prevalence of post-traumatic stress disorder (PTSD) in the general population is unavoidable and it seems that people who are suffering from severe psychiatric disorders especially schizophrenia, are more vulnerable to traumatic exposure and consequently to post traumatic stress disorder. The present work aims at determining the prevalence and the characteristics of the association between schizophrenia and PTSD since it isn't well known in Morocco.

MATERIALS AND METHODS

We conducted a descriptive and analytical cross-sectional study over a period of three months from October 2019 to December 2019 at the Department of Mental Health and Psychiatric Diseases of the University Hospital Center Mohammed VI of Oujda.

RESULTS

The number of patients included in our study was 187 and the majority of them were male with a percentage of 76%. Several variables were evaluated. The prevalence of PTSD in the patients included in our study is 14%. In addition, the statistically significant variables were the presence of a stressful event (p = 0,001), the positive schizophrenia symptom score (PANSS P) (p = 0,031), the negative schizophrenia symptom score (PANSS N) (p = 0,005), the general schizophrenia symptom score (PANSS G) (p = 0,021), suicide risk (p < 0,001), and the presence of depression (p = 0,004).

CONCLUSION

The comorbidity schizophrenia-PTSD exists with non-negligible prevalence. The risks of non-diagnosis of this comorbidity could lead to inappropriate treatments, a multiplication of care with no notable clinical improvement, poor therapeutic compliance and the alteration in the patients' quality of life.

摘要

未标注

创伤后应激障碍(PTSD)在普通人群中的患病率是不可避免的,而且似乎患有严重精神疾病尤其是精神分裂症的人更容易遭受创伤暴露,进而更容易患上创伤后应激障碍。由于在摩洛哥对精神分裂症与创伤后应激障碍之间的关联的患病率和特征尚不为人所知,本研究旨在确定这两者之间的关联。

材料与方法

我们于2019年10月至2019年12月的三个月期间,在乌季达穆罕默德六世大学医院中心心理健康与精神疾病科进行了一项描述性和分析性横断面研究。

结果

我们研究纳入的患者数量为187例,其中大多数为男性,占比76%。评估了多个变量。我们研究中纳入的患者创伤后应激障碍的患病率为14%。此外,具有统计学意义的变量包括存在应激事件(p = 0.001)、精神分裂症阳性症状评分(PANSS P)(p = 0.031)、精神分裂症阴性症状评分(PANSS N)(p = 0.005)、精神分裂症总体症状评分(PANSS G)(p = 0.021)、自杀风险(p < 0.001)以及存在抑郁(p = 0.004)。

结论

精神分裂症与创伤后应激障碍的共病患病率不可忽视。未能诊断出这种共病的风险可能导致治疗不当、护理增多但临床无明显改善、治疗依从性差以及患者生活质量下降。

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本文引用的文献

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Treating trauma in psychosis with EMDR: a pilot study.EMDR 治疗精神病性创伤:一项初步研究。
J Behav Ther Exp Psychiatry. 2012 Mar;43(1):664-71. doi: 10.1016/j.jbtep.2011.09.011. Epub 2011 Sep 17.

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