Khan Mohammad Aasim, Almas Talal, Ullah Muneeb, Alkhattab Maha, Shaikh Fathema, Shaikh Sufyan, Bagwe Isha, Antony Meetty, Khedro Tarek, Nagarajan Vikneswaran Raj, Ramjohn Joshua, Alsufyani Reema, Almubarak Dana, Al-Awaid Abdulla Hussain, Alsufyani Majid, Nagarajan Dhineswaran Raj, Khan Muhammad Omer, Huang Helen, Oruk Mert, Samy Arjun, Alqallaf Nagi, Shafi Adil, Adeel Aqsa, Khan Muhammad Kashif
Khyber Medical College, Peshawar, Pakistan.
RCSI University of Medicine and Health Sciences, Dublin, Ireland.
Ann Med Surg (Lond). 2022 Apr 19;77:103648. doi: 10.1016/j.amsu.2022.103648. eCollection 2022 May.
Pancreatic pseudocysts remain a feared complication of acute or chronic pancreatitis and are often characterized by collections of fluids due to underlying damage to the pancreatic ducts, culminating in a walled-off region bereft of an epithelial layer but surrounded by granulation tissue. While fungal infections of pancreatic pseudocysts are rarely encountered, candida albicans remains the most frequently implicated organism.
A 55-year-old male presented with pain in the left-hypochondriac region, accompanied by non-bilious emesis and nausea. Interestingly, the patient also tested positive for a COVID-19 infection. Investigative workup divulged enhancing pancreatic walls with a radiologic impression consistent with a pancreatic pseudocyst. An ultrasound-guided external drainage was performed; the drainage was conducted unremarkably, with the resultant fluid collection revealing the presence of Candida Glabrata. The patient was commenced on antifungal therapy and continues to do well to date.
Infectious ailments of pancreatic pseudocysts remain a widely known complication of acute pancreatitis. While it is rare, fungal infection is a crucial consideration for patients with pancreatic pseudocysts, especially in the context of a lack of an adequate response to antibiotics, deterioration, comorbidities, and immunocompromised states.
Rapid identification of the microbe responsible for pancreatic pseudocyst infection is vital for time-sensitive treatment and a more rapid recovery, curbing associated morbidity and mortality.
胰腺假性囊肿仍然是急性或慢性胰腺炎令人担忧的并发症，其特征通常是由于胰腺导管潜在损伤导致液体聚集，最终形成一个没有上皮层但被肉芽组织包围的包裹性区域。虽然胰腺假性囊肿的真菌感染很少见，但白色念珠菌仍然是最常涉及的病原体。
一名55岁男性因左季肋区疼痛就诊，伴有非胆汁性呕吐和恶心。有趣的是，该患者新冠病毒感染检测呈阳性。检查发现胰腺壁强化，影像学表现符合胰腺假性囊肿。进行了超声引导下的外引流；引流过程顺利，引流液中发现光滑念珠菌。患者开始接受抗真菌治疗，并至今情况良好。
胰腺假性囊肿的感染性疾病仍然是急性胰腺炎广为人知的并发症。虽然罕见，但真菌感染是胰腺假性囊肿患者的一个关键考虑因素，特别是在对抗生素反应不足、病情恶化、合并症和免疫功能低下的情况下。
快速识别导致胰腺假性囊肿感染的微生物对于及时治疗和更快康复至关重要，可降低相关的发病率和死亡率。
