Institute for Advanced Study, Shenzhen University, Shenzhen, 518060, China.
School of Engineering, Macquarie University, Sydney, NSW, 2109, Australia.
J Nanobiotechnology. 2022 May 28;20(1):246. doi: 10.1186/s12951-022-01471-0.
Liquid metal (LM) can be integrated into microfluidic channel, bringing new functionalities of microfluidics and opening a new window for soft microfluidic electronics, due to the superior advantages of the conductivity and deformability of LMs. However, patterning the LMs into microfluidic channels requires either selective surface wetting or complex fabrication process.
In this work, we develop a method to pattern the LMs onto the soft elastomer via soft lithographic process for fabrication of soft microfluidic sensors without the surface modification, bulky facilities, and complicated processes. The combination of the interfacial hydrogen bond and surface tension enables the LM patterns transfer to the soft elastomer. The transferred LM patterns with an ellipse-like cross-section further improve the stability under the mechanical deformation. Three proof-of-concept experiments were conducted to demonstrate the utilization of this method for development of thermochromic sensors, self-powered capacity sensors and flexible biosensor for glucose detection.
In summary, the proposed method offers a new patterning method to obtain soft microfluidic sensors and brings new possibilities for microfluidics-related wearable devices.
液态金属 (LM) 可以集成到微流道中,由于 LM 的导电性和可变形性的优势,为微流控带来新的功能,并为软微电子学开辟了新的窗口。然而,将 LM 图案化为微流道需要选择性表面润湿或复杂的制造工艺。
在这项工作中,我们通过软光刻工艺开发了一种将 LM 图案转移到软弹性体上的方法,用于制造无需表面改性、大型设备和复杂工艺的软微流控传感器。界面氢键和表面张力的结合使 LM 图案能够转移到软弹性体上。具有椭圆形横截面的转移 LM 图案进一步提高了在机械变形下的稳定性。进行了三个概念验证实验,以证明该方法用于开发热敏传感器、自供电电容传感器和用于葡萄糖检测的柔性生物传感器的应用。
总之,所提出的方法提供了一种获得软微流控传感器的新图案化方法,并为与微流控相关的可穿戴设备带来了新的可能性。