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适量饮酒与预防抑郁:批判性综述。

Moderate alcohol consumption and depression prevention: A critical review.

机构信息

Institut Universitari d’Investigació en Ciències de la Salut (IUNICS), Universitad de las Islas Baleares, Carretera de Valldemossa, km 7.5, 07122 Palma de Mallorca, España. Health Research Institute of the Balearic Islands (IdiSBa), 07120 Palma de Mallorca, Spain.

Institut Universitari d’Investigació en Ciències de la Salut (IUNICS), Universitad de las Islas Baleares, Carretera de Valldemossa, km 7.5, 07122 Palma de Mallorca, España Health Research Institute of the Balearic Islands (IdiSBa), 07120 Palma de Mallorca, Spain.

出版信息

Actas Esp Psiquiatr. 2022 May;50(3):126-133. Epub 2022 May 1.

PMID:35643971
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10828854/
Abstract

There is a clear consensus that alcohol use disorders are associated with poorer outcomes concerning depression, and that drinking alcohol shouldn`t be recommended because of the risk of dependence. Until recently, literature focused almost exclusively on patients with alcohol use disorders and excludes patients with moderate alcohol use (MAU). It’s has been shown that MAU can prevent or improve the evolution of chronic diseases such as cardiovascular diseases, but several researchers have suggested that there is no safe level of alcohol drinking due to other effects on health. Nevertheless, there is some evidence regarding the antidepressant effect of moderate alcohol consumption. This critical review aims to sum up the direction and tendency of current research on the effect of MAU on depression and relate the causal or confounders factors that might explain the results.

摘要

人们普遍认为,酒精使用障碍与抑郁的预后较差有关,而且由于存在依赖的风险,不应推荐饮酒。直到最近,文献几乎完全集中在酒精使用障碍患者身上,而排除了中度酒精使用(MAU)患者。已经表明,MAU 可以预防或改善心血管疾病等慢性疾病的发展,但一些研究人员认为,由于对健康的其他影响,不存在安全的饮酒水平。然而,关于中度饮酒的抗抑郁作用有一些证据。本批判性综述旨在总结当前关于 MAU 对抑郁影响的研究方向和趋势,并涉及可能解释结果的因果或混杂因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59e7/10828854/c9341e8b393e/ActEsp-50-3-126-133-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59e7/10828854/c9341e8b393e/ActEsp-50-3-126-133-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59e7/10828854/c9341e8b393e/ActEsp-50-3-126-133-F1.jpg

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Behav Neurol. 2021 Mar 25;2021:5681913. doi: 10.1155/2021/5681913. eCollection 2021.
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Low-to-Moderate Alcohol Intake Associated with Lower Risk of Incidental Depressive Symptoms: A Pooled Analysis of Three Intercontinental Cohort Studies.低至中度饮酒与偶发性抑郁症状风险降低相关:三项洲际队列研究的汇总分析。
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酒精使用障碍与重度抑郁症共病的物种差异:一项叙述性综述。
Alcohol Clin Exp Res (Hoboken). 2025 Apr;49(4):712-724. doi: 10.1111/acer.70015. Epub 2025 Mar 9.
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