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埃塞俄比亚阿姆哈拉州德布雷马科斯综合专科医院抗逆转录病毒治疗门诊成年患者的抑郁症状及相关因素

Depressive symptoms and associated factors among adults attending antiretroviral therapy clinic in Debre Markos comprehensive specialized hospital, Amhara, Ethiopia.

作者信息

Amha Haile, Denekew Bethlehem, Asnakew Sintayehu

机构信息

Department of Nursing, College of Health Science, Debre Markos University, Debre Markos, Ethiopia.

Department of Psychiatry, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.

出版信息

SAGE Open Med. 2022 May 23;10:20503121221100992. doi: 10.1177/20503121221100992. eCollection 2022.

DOI:10.1177/20503121221100992
PMID:35646359
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9134454/
Abstract

OBJECTIVE

This study aimed to assess the prevalence and associated factors of depressive symptoms among adults attending anti-retroviral therapy follow up at Debre Markos Comprehensive Specialized Hospital.

METHODS

Institution-based cross-sectional study was conducted, and a systematic sampling technique was used to select the 266 participants. Depressive symptoms were assessed by using patient health questionnaire 9. A binary logistic regression analysis with an odds ratio and a 95% confidence interval was used to assess the strength of associations in SPSS version 20 and a p-value < 0.05 was considered as statistically significant.

RESULTS

In this study, the prevalence of depressive symptoms among HIV-positive individuals was 39.1% with 95% confidence interval (33.7%-45.3%). Multivariable analysis showed that participants who had age group > 40 (adjusted odds ratio = 5.26, 95% confidence interval (2.24-12.35)), presence of perceived stigma and discrimination (adjusted odds ratio = 7.5, 95% confidence interval = (3.77-14.9)), poor medication adherence (adjusted odds ratio = 6.05, 95% confidence interval = (2.86-12.80)), and poor social support (adjusted odds ratio = 2.53, 95% confidence interval = (1.25-5.12)) were significantly associated with depression.

CONCLUSION

The prevalence of depressive symptoms in this study was found to be significantly high. Age > 40 years old, the presence of perceived stigma and discrimination, poor medication adherence, and a lack of social support were found to be associated factors of depressive symptoms. It would be better for clinicians to give special emphasis to those patients who were stigmatized, who had compliance problems, and poor social support.

摘要

目的

本研究旨在评估德布雷马科斯综合专科医院接受抗逆转录病毒治疗随访的成年人中抑郁症状的患病率及相关因素。

方法

开展基于机构的横断面研究,采用系统抽样技术选取266名参与者。使用患者健康问卷9评估抑郁症状。在SPSS 20版中采用二元逻辑回归分析及比值比和95%置信区间来评估关联强度,p值<0.05被认为具有统计学意义。

结果

本研究中,HIV阳性个体抑郁症状的患病率为39.1%,95%置信区间为(33.7%-45.3%)。多变量分析显示,年龄>40岁的参与者(调整后的比值比=5.26,95%置信区间为(2.24-12.35))、存在感知到的耻辱和歧视(调整后的比值比=7.5,95%置信区间=(3.77-14.9))、药物依从性差(调整后的比值比=6.05,95%置信区间=(2.86-12.80))以及社会支持差(调整后的比值比=2.53,95%置信区间=(1.25-5.12))与抑郁症显著相关。

结论

本研究发现抑郁症状的患病率显著较高。年龄>40岁、存在感知到的耻辱和歧视、药物依从性差以及缺乏社会支持被发现是抑郁症状的相关因素。临床医生最好特别关注那些受到耻辱对待、有依从性问题且社会支持差的患者。

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