Aĭrapetiants M G, Mekhedova A Ia, Kozlovskaia M M, Neznamov G G
Zh Vyssh Nerv Deiat Im I P Pavlova. 1986 Nov-Dec;36(6):1131-8.
Introduction in tests with positive (alimentary) reinforcement, of elements of uncertainty and of "collision" of motivations, and carrying out of a series of experiments on dogs under such conditions during 2-4 weeks, led to the development of heavy and stable neurotic states. They were characterized by disturbances of emotional-motivational sphere, suppression of conditioned activity, somatovegetative dysfunctions. Preparations of atypical antidepressants (emovit and new benzamine derivate) reduced neurotic manifestations. The rate of reduction depended on the spectrum of neuro-psychotropic activity and properties of pathological states in dogs.