Department of Environmental Management and Toxicology, Faculty of Life Sciences, University of Benin, Benin City, Nigeria.
Department of Environmental Management and Toxicology, College of Environmental Resources Management, Federal University of Agriculture, Abeokuta, Nigeria.
Environ Monit Assess. 2022 Jun 1;194(7):467. doi: 10.1007/s10661-022-10135-3.
The relationship between indoor particulate matter and asthma in children was assessed in this study. Forty-five (45) locations were randomly selected across the five local government areas in Benin City, Edo State, for air quality assessment. Indoor and outdoor particulates (PM, PM, and PM) were monitored monthly using a handheld BLATN particulate sampler (Br-Smart-126S series). Reported clinical cases of asthma in children from 2008 to 2017 were collected from two major hospitals in the metropolis. The data obtained were analysed with SPSS for Windows version 21.0. The average concentrations of indoor and ambient PM ranged between 10.7-26.2 and 19.0-49.4 µg/m (PM), 27.4-59.6 and 45.6-93.0 µg/m (PM), and 33.5-67.9 and 60.9-106.1 µg/m (PM) in the wet and dry seasons. PM and PM concentrations were observed above the WHO standards. Indoor particulate concentration was significantly (p = 0.001-0.012) higher in the dry season across the locations. Outdoor PM correlated positively (R = 0.568-0.855, p < 0.05; R = 0.322-0.724, p < 0.001) with their corresponding indoor PM concentration. The hazard ratio (HR) values of PM and PM exceeded 1 in all the sampling locations during the dry season, while the mean total hazard ratio (THR) of both PM metrics was considerably higher during the dry season than in the wet season. Indoor PM concentrations showed a significant positive correlation with reported cases of asthma (R = 0.498-0.542, p < 0.001) and accounted for 40.6% of the asthma cases during the dry season. The study showed that children in the selected households are at risk of increased asthma exacerbation due to exposure to particulate matter pollution.
本研究评估了室内颗粒物与儿童哮喘之间的关系。在埃多州贝宁城的五个地方政府区随机选择了 45 个地点进行空气质量评估。每月使用手持式 BLATN 颗粒物采样器（Br-Smart-126S 系列）监测室内和室外颗粒物（PM、PM 和 PM）。从 2008 年到 2017 年，从大都市的两家主要医院收集了儿童哮喘的报告临床病例。使用 Windows 版 SPSS 21.0 分析获得的数据。室内和环境 PM 的平均浓度在雨季和旱季分别为 10.7-26.2 和 19.0-49.4μg/m（PM）、27.4-59.6 和 45.6-93.0μg/m（PM）和 33.5-67.9 和 60.9-106.1μg/m（PM）。PM 和 PM 浓度均高于世界卫生组织标准。在旱季，所有地点的室内颗粒物浓度均明显（p=0.001-0.012）更高。室外 PM 与室内 PM 浓度呈正相关（R=0.568-0.855，p<0.05；R=0.322-0.724，p<0.001）。旱季所有采样地点的 PM 和 PM 危害比（HR）值均超过 1，而旱季两种 PM 指标的平均总危害比（THR）明显高于雨季。室内 PM 浓度与哮喘报告病例呈显著正相关（R=0.498-0.542，p<0.001），且在旱季占哮喘病例的 40.6%。研究表明，由于暴露于颗粒物污染，选择家庭中的儿童患哮喘恶化的风险增加。
