Jonsson L O, Johansson S L, Zetterström H
Acta Anaesthesiol Scand. 1987 Feb;31(2):179-86. doi: 10.1111/j.1399-6576.1987.tb02545.x.
Thirty-four adults were studied during halothane anaesthesia with spontaneous breathing, while undergoing orthopaedic surgery. They were randomly divided into two groups according to whether the Bain (n = 18) or the Lack (n = 16) system was used. Respiratory flows were recorded and arterial blood gases drawn at different fresh gas flows (VF). The values obtained were compared with those recorded under non-rebreathing conditions (NRC). In the Bain system the proportion of rebreathers was 0.22, 0.25, 0.55 and 0.83 when the VF was 175, 150, 125 and 100 ml X min-1 X kg-1 body weight (b.w.), respectively. In the Lack system these proportions were 0.43, 0.55 and 0.92 at VF of 85, 70 and 55 ml X min-1 kg-1 b.w., respectively. The ventilatory response to rebreathing was an increase in minute ventilation (VE), keeping the partial pressure of arterial carbon dioxide (PACO2) almost unaltered. In the Bain system the VE X kg-1 X b.w. thus increased by 18% and 38% at VF of 125 and 100 ml X min-1 X kg-1 b.w., respectively, when compared to NRC (P less than 0.05). The corresponding increases in the Lack system were 15% and 37% at VF of 70 and 55 ml X min-1 X kg-1 b.w., respectively (P less than 0.01). In the Lack group also the PACO2 increased by 6% when a VF of 55 ml X min-1 X kg-1 b.w. was used compared to the value obtained under NRC (P less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
34名成年人在氟烷麻醉下自主呼吸，同时接受骨科手术。根据使用的是贝恩系统（n = 18）还是拉克系统（n = 16），他们被随机分为两组。记录不同新鲜气体流量（VF）下的呼吸流量，并采集动脉血气。将获得的值与非再呼吸条件（NRC）下记录的值进行比较。在贝恩系统中，当VF分别为175、150、125和100 ml·min⁻¹·kg⁻¹体重（b.w.）时，再呼吸者的比例分别为0.22、0.25、0.55和0.83。在拉克系统中，当VF分别为85、70和55 ml·min⁻¹·kg⁻¹ b.w.时，这些比例分别为0.43、0.55和0.92。对再呼吸的通气反应是分钟通气量（VE）增加，同时动脉血二氧化碳分压（PACO₂）几乎保持不变。在贝恩系统中，与NRC相比，当VF为125和100 ml·min⁻¹·kg⁻¹ b.w.时，VE·kg⁻¹·b.w.分别增加了18%和38%（P < 0.05）。在拉克系统中，当VF为70和55 ml·min⁻¹·kg⁻¹ b.w.时，相应的增加分别为15%和37%（P < 0.01）。在拉克组中，当使用55 ml·min⁻¹·kg⁻¹ b.w.的VF时，与NRC下获得的值相比，PACO₂也增加了6%（P < 0.05）。（摘要截短至250字）
