Utsalo S J
Acta Microbiol Hung. 1986;33(3):183-91.
One hundred and sixty strains of Staphylococcus aureus isolated from various clinical specimens were classified into groups: hospital staphylococci (HS) or community staphylococci (CS), based on the clinico-ecological circumstances of isolation. Fifty strains from both groups were tested for the minimum inhibitory concentration (MIC) of penicillin G, streptomycin, tetracycline, chloramphenicol, mercuric chloride, disodium hydrogen arsenate, silver nitrate and sodium bisulphite. Four representative strains from each group were further studied for resistance to "in-use" dilutions of 4 disinfectants (Dettol, Izal, Savlon and Chlohexidine), heat stress and the effect of solar radiation in sand cultures. All HS and 31.8% of CS were resistant to penicillin and ampicillin and produced penicillinase. HS had higher MICs of antibiotics and metallic ions and longer bactericidal times with disinfectants than CS. Resistance to thermal stress varied within each group but survival in sand cultures under solar radiation appeared to be influenced by multiple factors to which community staphylococci were probably better adapted.
从各种临床标本中分离出的160株金黄色葡萄球菌，根据分离的临床生态情况分为医院葡萄球菌（HS）或社区葡萄球菌（CS）两组。对两组中的50株菌株进行了青霉素G、链霉素、四环素、氯霉素、氯化汞、砷酸氢二钠、硝酸银和亚硫酸氢钠的最低抑菌浓度（MIC）测试。对每组中的4株代表性菌株进一步研究了其对4种消毒剂（滴露、伊扎尔、萨伏隆和洗必泰）“实际使用”稀释液的抗性、热应激以及沙培中太阳辐射的影响。所有HS菌株和31.8%的CS菌株对青霉素和氨苄青霉素耐药并产生青霉素酶。HS菌株对抗生素和金属离子的MIC更高，对消毒剂的杀菌时间比CS菌株更长。每组内热应激抗性各不相同，但在太阳辐射下沙培中的存活似乎受多种因素影响，社区葡萄球菌可能对此类因素适应性更强。
