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婴幼儿牛奶蛋白过敏的辅食添加与营养状况

Complementary feeding and nutritional status of infants on cow's milk proteins elimination diet.

机构信息

Universidade Federal de São Paulo, São Paulo, SP, Brasil.

Unidade Básica de Saúde de Fátima, Belém, PA, Brasil.

出版信息

Rev Paul Pediatr. 2022 May 27;40:e20200429. doi: 10.1590/1984-0462/2022/40/2020429IN. eCollection 2022.

Abstract

OBJECTIVE

To evaluate the diet and nutritional status of infants on an elimination diet of cow's milk proteins.

METHODS

Observational and cross-sectional study that compared: Infants on a cow's milk protein elimination diet (n=60) assisted at a hypoallergenic formula distribution unit and a control group of same age and gender without dietary restrictions (n=60). Age ranged from 6 to 24 months. The diet was evaluated using the 24-hour food survey and weight and height were measured.

RESULTS

The macronutrient intake of both groups reached nutritional recommendations. The proportions of infants in the group of elimination of cow's milk proteins with insufficient intake were lower, compared to controls, for iron (13.3 and 31.7%; p=0.029), zinc (5.0 and 18.3%; p=0.047), and vitamin D (25.0 and 71.7%; p<0.001). The hypoallergenic formula contributed to a greater supply of nutrients than dairy foods for the control group. Between 12 and 24 months, the number of infants on a restriction diet who never consumed meat, fish, cereals, and eggs was higher than in the control group (p<0.05). The length-age Z scores in infants on a cow's milk protein elimination diet (-0.4±1.6) were lower (p=0.039) than in the control group (+0.2±1.3).

CONCLUSIONS

The diet of infants with exclusion of cow's milk protein was adequate despite the delay in the introduction of some complementary foods. Infants on an elimination cow's milk protein diet showed lower linear growth without weight deficit.

摘要

目的

评估牛奶蛋白过敏婴儿的饮食和营养状况。

方法

本研究为观察性和横断面研究,比较了 60 名接受低敏配方奶粉的牛奶蛋白排除饮食婴儿和 60 名年龄、性别相同且无饮食限制的对照组婴儿。年龄范围为 6 至 24 个月。采用 24 小时膳食调查评估饮食,测量体重和身高。

结果

两组的宏量营养素摄入量均达到营养推荐量。与对照组相比,牛奶蛋白排除组摄入不足的婴儿比例较低,包括铁(13.3%和 31.7%;p=0.029)、锌(5.0%和 18.3%;p=0.047)和维生素 D(25.0%和 71.7%;p<0.001)。低敏配方为对照组提供了比乳制品更多的营养。在 12 至 24 个月期间,限制饮食的婴儿中从未食用肉类、鱼类、谷物和蛋类的婴儿数量多于对照组(p<0.05)。牛奶蛋白排除饮食的婴儿的长度年龄 Z 评分(-0.4±1.6)较低(p=0.039),而对照组的评分(+0.2±1.3)较高。

结论

尽管一些补充食品的引入延迟,但排除牛奶蛋白的婴儿饮食仍充足。牛奶蛋白排除饮食的婴儿线性生长较低,而体重无不足。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1084/9150899/64ef616f3213/1984-0462-rpp-40-e2020429-gf01.jpg

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