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使用合成代谢雄激素类固醇与精神病态、冒险行为、愤怒和身体问题有关。

Anabolic-androgenic steroid use is associated with psychopathy, risk-taking, anger, and physical problems.

机构信息

Department of Psychology, New York University, New York, NY, USA.

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

出版信息

Sci Rep. 2022 Jun 1;12(1):9133. doi: 10.1038/s41598-022-13048-w.

Abstract

Previous research has uncovered medical and psychological effects of anabolic-androgenic steroid (AAS) use, but the specific relationship between AAS use and risk-taking behaviors as well as between AAS use and psychopathic tendencies remains understudied. To explore these potential relationships, we anonymously recruited 492 biologically male, self-identified bodybuilders (median age 22; range 18-47 years) from online bodybuilding fora to complete an online survey on Appearance and Performance Enhancing Drug (APED) use, psychological traits, lifestyle choices, and health behaviors. We computed odds ratios and 95% confidence intervals using logistic regression, adjusting for age, race, education, exercise frequency, caloric intake, and lean BMI. Bodybuilders with a prior history of AAS use exhibited heightened odds of psychopathic traits, sexual and substance use risk-taking behaviors, anger problems, and physical problems compared to those with no prior history of AAS use. This study is among the first to directly assess psychopathy within AAS users. Our results on risk-taking, anger problems, and physical problems are consistent with prior AAS research as well as with existing frameworks of AAS use as a risk behavior. Future research should focus on ascertaining causality, specifically whether psychopathy is a risk associated with or a result of AAS use.

摘要

先前的研究已经揭示了合成代谢雄激素类固醇(AAS)使用对身体的医学影响和心理影响,但 AAS 使用与冒险行为之间的具体关系,以及 AAS 使用与精神病倾向之间的关系仍有待研究。为了探索这些潜在的关系,我们匿名招募了 492 名来自在线健身论坛的自我认同的男性健美运动员(中位年龄 22 岁;年龄范围 18-47 岁),要求他们完成一项关于使用外貌和表现增强药物(APED)、心理特征、生活方式选择和健康行为的在线调查。我们使用逻辑回归计算了优势比和 95%置信区间,并调整了年龄、种族、教育程度、运动频率、热量摄入和瘦体重 BMI。与没有使用 AAS 历史的健美运动员相比,有使用 AAS 历史的健美运动员表现出更高的精神病特征、性和药物使用冒险行为、愤怒问题和身体问题的几率。这项研究是首次直接在 AAS 用户中评估精神病。我们关于冒险行为、愤怒问题和身体问题的结果与先前的 AAS 研究以及 AAS 使用作为一种风险行为的现有框架一致。未来的研究应重点确定因果关系,特别是精神病是否是与 AAS 使用相关的风险因素,或者是 AAS 使用的结果。

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