Bellamkonda Amulya, Chowdhury Tutul, Shankar Malavika, Gousy Nicole
Internal Medicine, One Brooklyn Health System, Brooklyn, USA.
Medicine, American University of Antigua, New York, USA.
Cureus. 2022 Apr 30;14(4):e24619. doi: 10.7759/cureus.24619. eCollection 2022 Apr.
Dialysis disequilibrium syndrome (DDS) is a neurological disorder with varying severity which is primarily caused by the rapid removal of urea during hemodialysis, which was first described in the literature in 1962. Common risk factors are extreme age, high blood urea nitrogen, sudden change in dialysis regimen, presence of other conditions causing cerebral edema, preexisting neurological diseases, and increased permeability of the blood-brain barrier. Understanding these risk factors and preventing the syndrome is crucial as no specific treatment guideline has been established yet. In this case report, we are presenting a case with a conglomeration of clinical attributes suggesting DDS.
透析失衡综合征(DDS)是一种严重程度各异的神经系统疾病,主要由血液透析过程中尿素的快速清除引起,该疾病于1962年首次在文献中被描述。常见的风险因素包括高龄、高血尿素氮、透析方案突然改变、存在其他导致脑水肿的情况、既往存在的神经系统疾病以及血脑屏障通透性增加。由于尚未建立具体的治疗指南,了解这些风险因素并预防该综合征至关重要。在本病例报告中,我们呈现了一例具有提示DDS的一系列临床特征的病例。