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透析失衡综合征:血液透析罕见的严重并发症及有效管理

Dialysis Disequilibrium Syndrome: Rare Serious Complication of Hemodialysis and Effective Management.

作者信息

Adapa Sreedhar, Konala Venu Madhav, Aeddula Narothama Reddy, Gayam Vijay, Naramala Srikanth

机构信息

Nephrology, The Nephrology Group, Visalia, USA.

Internal Medicine/ Hematology and Oncology, Ashland Bellefonte Cancer Center, Ashland, USA.

出版信息

Cureus. 2019 Jun 25;11(6):e5000. doi: 10.7759/cureus.5000.

Abstract

Dialysis disequilibrium syndrome (DDS) is an extremely rare central nervous system complication that occurs in patients receiving hemodialysis and can be potentially fatal. The prognosis is poor when this manifests with serious neurological manifestations like seizures and obtundation. Evidence in effective management is sparse. Herein, we present the case of a patient who developed seizures and altered mental status during hemodialysis. The patient successfully recovered with the administration of mannitol and 3% hypertonic saline without any long-term neurologic sequelae.

摘要

透析失衡综合征(DDS)是一种极其罕见的中枢神经系统并发症,发生于接受血液透析的患者,可能会危及生命。当出现癫痫发作和意识模糊等严重神经症状时,预后较差。有效治疗的证据很少。在此,我们报告一例患者在血液透析过程中出现癫痫发作和精神状态改变。该患者通过使用甘露醇和3%高渗盐水成功康复,未留下任何长期神经后遗症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56bf/6713250/0df51583313b/cureus-0011-00000005000-i01.jpg

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