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面向稳定型高碳酸血症慢性阻塞性肺疾病患者长期无创通气启动与控制的数字决策和工作流程支持系统。

Toward a digital decision- and workflow-support system for initiation and control of long-term non-invasive ventilation in stable hypercapnic COPD patients.

作者信息

Cornelissen Christian Gabriel, Winter Stefan, Keuchel Daniel, Spicher Nicolai, Boeckmann Britta, Stephan Christian, Saygi Tan, Windisch Wolfram, Vollmer Thomas, Dreher Michael

机构信息

Department of Pulmonology and Intensive Care Medicine, University Hospital Aachen, 52074 Aachen, Germany.

Philips GmbH Innovative Technologies Aachen, Aachen, Germany.

出版信息

Ther Adv Chronic Dis. 2022 May 25;13:20406223221099338. doi: 10.1177/20406223221099338. eCollection 2022.

Abstract

INTRODUCTION

Due to an increasing demand for the initiation and control of non-invasive ventilation (NIV), digital algorithms are suggested to support therapeutic decisions and workflows in an ambulatory setting. The DIGIVENT project established and implemented such algorithms for patients with chronic hypercapnic respiratory failure due to chronic obstructive pulmonary disease (COPD) by a predefined process.

METHODS

Based on long-term clinical experience and guideline recommendations as provided by the German Respiratory Society, detailed graphical descriptions of how to perform NIV in stable COPD patients were created. Subsequently, these clinical workflows were implemented in the Business Process Model and Notation (BPMN) as one tool to formalize these workflows serving as input for an executable digital implementation.

RESULTS

We succeeded in creating an executable digital implementation that reflects clinical decision-making and workflows in digital algorithms. Furthermore, we built a user-friendly graphical interface that allows easy interaction with the DIGIVENT support algorithms.

CONCLUSION

The DIGIVENT project established digital treatment algorithms and implemented a decision- and workflow-support system for NIV whose validation in a clinical cohort is planned.

摘要

引言

由于对无创通气(NIV)启动和控制的需求不断增加,建议采用数字算法来支持门诊环境中的治疗决策和工作流程。DIGIVENT项目通过预定义的流程,为慢性阻塞性肺疾病(COPD)导致的慢性高碳酸血症呼吸衰竭患者建立并实施了此类算法。

方法

基于德国呼吸学会提供的长期临床经验和指南建议,创建了关于如何在稳定的COPD患者中进行无创通气的详细图形描述。随后,这些临床工作流程在业务流程模型和符号(BPMN)中得以实现,BPMN作为一种将这些工作流程形式化的工具,为可执行的数字实现提供输入。

结果

我们成功创建了一个可执行的数字实现,该实现反映了数字算法中的临床决策和工作流程。此外,我们构建了一个用户友好的图形界面,便于与DIGIVENT支持算法进行交互。

结论

DIGIVENT项目建立了数字治疗算法,并实施了一个用于无创通气的决策和工作流程支持系统,计划在临床队列中对其进行验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa3f/9149610/cbe5c4a6dcaf/10.1177_20406223221099338-fig1.jpg

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