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银纳米粒子的绿色合成及其抗癌作用研究综述

A Review on Green Synthesis of Silver Nanoparticles and its Role against Cancer.

机构信息

Department of Pharmaceutical Sciences, Chaudhary Bansi Lal University, Bhiwani (HR), India.

Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.

出版信息

Curr Top Med Chem. 2022;22(18):1460-1471. doi: 10.2174/1568026622666220601165005.

DOI:10.2174/1568026622666220601165005
PMID:35652404
Abstract

Cancer is a fatal disease with a collection of related diseases in various body parts. The conventional therapies cannot show the desired results of treatment due to their imprecise targeting, deprived drug delivery, and side effects. Therefore, it is required to make the drug engineered so that it can target only cancerous cells and inhibit its growth and proliferation. Nanotechnology is a technology that can target and differentiate between cancerous cells and the body's normal cells. Silver itself is a good anticancer and antibacterial agent and employing it with phytochemicals with anticancer properties, and nanotechnology can give the best approach for the treatment. The synthesis of silver nanoparticles using plant extracts is an economical, energy-efficient, low-cost approach, and it doesn't need any hazardous chemicals. In the present review, we discussed different methods of synthesis of silver nanoparticles using herbal extracts and their role against cancer therapy along with the synergistic role of silver and plant extracts against cancer in the formulation.

摘要

癌症是一种致命的疾病,它涉及到身体各个部位的一系列相关疾病。由于传统疗法靶向不准确、药物输送受限以及存在副作用,因此无法达到理想的治疗效果。因此,需要对药物进行设计,使其能够专门针对癌细胞,并抑制其生长和增殖。纳米技术是一种能够靶向区分癌细胞和正常细胞的技术。银本身就是一种很好的抗癌和抗菌剂,将其与具有抗癌特性的植物化学物质结合使用,并结合纳米技术,可以为治疗提供最佳方法。使用植物提取物合成银纳米粒子是一种经济、节能、低成本的方法,且不需要任何危险的化学物质。在本综述中,我们讨论了使用草药提取物合成银纳米粒子的不同方法,以及它们在癌症治疗中的作用,以及银和植物提取物在制剂中对癌症的协同作用。

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