Zhongguo Dang Dai Er Ke Za Zhi. 2022 Jun 15;24(6):597-603. doi: 10.7499/j.issn.1008-8830.2203190.
Kawasaki disease (KD) is one of the common acquired heart diseases in children aged <5 years and is an acute systemic vasculitis. After nearly 60 years of research, intravenous immunoglobulin combined with oral aspirin has become the first-line treatment for the prevention of coronary artery lesion in acute KD; however, there are still controversies over the role and optimal dose of aspirin. The consensus was formulated based on the latest research findings of KD treatment in China and overseas and comprehensive discussion of pediatric experts in China and put forward recommendations on the dose, usage, and course of aspirin treatment in the first-line treatment of KD.
川崎病(KD)是5岁以下儿童常见的后天性心脏病之一,是一种急性全身性血管炎。经过近60年的研究,静脉注射免疫球蛋白联合口服阿司匹林已成为预防急性KD冠状动脉病变的一线治疗方法;然而,阿司匹林的作用和最佳剂量仍存在争议。本共识基于国内外KD治疗的最新研究结果以及国内儿科专家的全面讨论而制定,针对KD一线治疗中阿司匹林治疗的剂量、用法和疗程提出了建议。