Zhongguo Dang Dai Er Ke Za Zhi. 2023 Dec 15;25(12):1198-1210. doi: 10.7499/j.issn.1008-8830.2309038.
Kawasaki disease (KD) is an acute self-limiting vasculitis, and it is the most common cause of acquired heart disease in children under 5 years old. One of the improvement goals in pediatric quality control work for the year 2023, as announced by the National Health Commission, is to reduce the incidence of cardiac events and KD-related mortality in children with KD. In order to standardize the diagnosis, treatment, and long-term management practices of KD in China, and effectively prevent and reduce the incidence of coronary artery lesions and long-term adverse effects, the guideline working group followed the principles and methods outlined by the World Health Organization and referenced existing evidence and experiences to develop the "Evidence-based guidelines for the diagnosis and treatment of Kawasaki disease in children in China (2023)". The guidelines address the clinical questions regarding the classification and definition of KD, diagnosis of different types of KD, treatment during the acute phase of KD, application of echocardiography in identifying complications of KD, and management of KD combined with macrophage activation syndrome. Based on the best evidence and expert consensus, 20 recommendations were formulated, aiming to provide guidance and decision-making basis for healthcare professionals in the diagnosis and treatment of KD in children.
川崎病(KD)是一种急性自限性血管炎,是5岁以下儿童获得性心脏病的最常见病因。国家卫生健康委公布的2023年儿童医疗质量控制工作改进目标之一,是降低川崎病患儿心脏事件发生率及KD相关死亡率。为规范我国川崎病的诊断、治疗及长期管理实践,有效预防和降低冠状动脉病变发生率及远期不良影响,指南工作组遵循世界卫生组织提出的原则和方法,参考现有证据和经验,制定了《中国儿童川崎病诊断与治疗循证指南(2023年版)》。该指南针对川崎病的分类与定义、不同类型川崎病的诊断、川崎病急性期治疗、超声心动图在川崎病并发症识别中的应用以及川崎病合并巨噬细胞活化综合征的管理等临床问题进行阐述。基于最佳证据和专家共识,制定了20条推荐意见,旨在为儿童川崎病诊治的医疗专业人员提供指导和决策依据。