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离子通道的选择性和输运的量子相干性。

Quantum coherence on selectivity and transport of ion channels.

机构信息

Research Group on Foundations of Quantum Theory and Information, Department of Chemistry, Sharif University of Technology, P.O. Box 11365-9516, Tehran, Iran.

Sharif Quantum Center, Sharif University of Technology, Tehran, Iran.

出版信息

Sci Rep. 2022 Jun 2;12(1):9237. doi: 10.1038/s41598-022-13323-w.

DOI:10.1038/s41598-022-13323-w
PMID:35654822
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9163109/
Abstract

Recently, it has been suggested that ion channel selectivity filter may exhibit quantum coherence, which may be appropriate to explain ion selection and conduction processes. Potassium channels play a vital role in many physiological processes. One of their main physiological functions is the efficient and highly selective transfer of K ions through the membranes into the cells. To do this, ion channels must be highly selective, allowing only certain ions to pass through the membrane, while preventing the others. The present research is an attempt to investigate the relationship between hopping rate and maintaining coherence in ion channels. Using the Lindblad equation to describe a three-level system, the results in different quantum regimes are examined. We studied the distillable coherence and the second order coherence function of the system. The oscillation of distillable coherence from zero, after the decoherence time, and also the behavior of the coherence function clearly show the point that the system is coherent in ion channels with high throughput rates.

摘要

最近有人提出,离子通道选择性过滤器可能表现出量子相干性,这可能有助于解释离子的选择和传导过程。钾通道在许多生理过程中起着至关重要的作用。它们的主要生理功能之一是通过细胞膜高效且高度选择性地将 K 离子转移到细胞内。为此,离子通道必须具有高度的选择性,只允许某些离子通过膜,同时阻止其他离子通过。本研究试图探讨离子通道中跳跃率和保持相干性之间的关系。我们使用林德布拉德方程来描述一个三能级系统,研究了不同量子态下的结果。我们研究了系统的可提取相干性和二阶相干函数。相干函数的零点、退相干时间后的振荡以及相干函数的行为清楚地表明,在高通量率的离子通道中,系统是相干的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64da/9163109/f5dd224f2e04/41598_2022_13323_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64da/9163109/d48353cfdc82/41598_2022_13323_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64da/9163109/8009b1fb3544/41598_2022_13323_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64da/9163109/90bf3b8c9207/41598_2022_13323_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64da/9163109/4ab1c748267c/41598_2022_13323_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64da/9163109/f5dd224f2e04/41598_2022_13323_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64da/9163109/d48353cfdc82/41598_2022_13323_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64da/9163109/7dd67fe1bcab/41598_2022_13323_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64da/9163109/09d3e943b029/41598_2022_13323_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64da/9163109/8009b1fb3544/41598_2022_13323_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64da/9163109/90bf3b8c9207/41598_2022_13323_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64da/9163109/4ab1c748267c/41598_2022_13323_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64da/9163109/f5dd224f2e04/41598_2022_13323_Fig7_HTML.jpg

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