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3,4-亚甲基二氧甲基苯丙胺(“摇头丸”)中毒致难治性多器官功能衰竭的体外膜肺氧合支持

Extracorporeal Membrane Oxygenation Support in Refractory Multi-organ Failure by 3,4-Methylenedioxymethamphetamine Intoxication ("Ecstasy").

作者信息

Ruiz Victoria, Rosciani Foda, Bisso Indalecio Carboni, Heras Marcos Las

机构信息

Department of Intensive Care Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

出版信息

Indian J Crit Care Med. 2022 Summer;26(4):521-523. doi: 10.5005/jp-journals-10071-24187.

DOI:10.5005/jp-journals-10071-24187
PMID:35656060
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9067490/
Abstract

UNLABELLED

The substance known as 3,4-methylenedioxymethamphetamine (MDMA) that is commonly named ecstasy is a designer drug used for recreation. The intoxication for MDMA could generate hyperthermia, hepatotoxicity, acute renal failure, cardiovascular toxicity, hyponatremia, serotonin syndrome, coma, and, eventually could lead to, death. There is no antidote available, that is why the treatment is symptomatic and of advanced vital support until the resolution of the case. A case is presented of an adult with multi-organ failure secondary to intoxication for MDMA in whom it was decided to initiate support of oxygenation with extracorporeal membrane oxygenation as a bridge to recovery, with good results.

HOW TO CITE THIS ARTICLE

Ruiz V, Rosciani F, Bisso IC, Heras ML. Extracorporeal Membrane Oxygenation Support in Refractory Multi-organ Failure by 3,4-Methylenedioxymethamphetamine Intoxication ("Ecstasy"). Indian J Crit Care Med 2022;26(4):521-523.

摘要

未标注

被称为3,4-亚甲基二氧甲基苯丙胺(MDMA)、俗称摇头丸的物质是一种用于娱乐的合成毒品。MDMA中毒可导致高热、肝毒性、急性肾衰竭、心血管毒性、低钠血症、血清素综合征、昏迷,并最终可能导致死亡。目前尚无解毒剂,这就是为什么治疗是对症的且需要进行高级生命支持,直至病情缓解。本文介绍了一例因MDMA中毒继发多器官功能衰竭的成年患者,决定采用体外膜肺氧合进行氧合支持作为恢复的桥梁,效果良好。

如何引用本文

Ruiz V, Rosciani F, Bisso IC, Heras ML. 3,4-亚甲基二氧甲基苯丙胺(“摇头丸”)中毒所致难治性多器官功能衰竭的体外膜肺氧合支持。《印度重症医学杂志》2022;26(4):521-523。

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本文引用的文献

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Indian J Crit Care Med. 2020 May;24(5):365-366. doi: 10.5005/jp-journals-10071-23423.
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MDMA toxicity: management of acute and life-threatening presentations.摇头丸中毒:急性及危及生命情况的处理
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A Case of MDMA-Associated Cerebral and Pulmonary Edema Requiring ECMO.一例需要体外膜肺氧合治疗的摇头丸相关脑和肺水肿病例。
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Early extracorporeal membrane oxygenation for cardiovascular failure in a patient with massive chloroquine poisoning.早期体外膜肺氧合治疗一名大量氯喹中毒患者的心血管衰竭。
Am J Emerg Med. 2017 Feb;35(2):380.e3-380.e4. doi: 10.1016/j.ajem.2016.08.058. Epub 2016 Aug 30.
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ECMO: A ray of hope for young suicide victims with acute aluminum phosphide poisoning and shock.体外膜肺氧合:急性磷化铝中毒并休克的年轻自杀受害者的一线希望。
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Extracorporeal Membrane Oxygenation (ECMO) for Severe Toxicological Exposures: Review of the Toxicology Investigators Consortium (ToxIC).用于严重毒理学暴露的体外膜肺氧合(ECMO):毒理学研究联盟(ToxIC)综述
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CMAJ. 2001 Oct 2;165(7):917-28.
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