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兔全视网膜光凝术后锌和铜代谢的变化

Changes in the zinc and copper metabolism after panretinal photocoagulation in the rabbit.

作者信息

Silverstone B Z, Kristol L, Algur N, Berson D, Sternbuch J

出版信息

Ann Ophthalmol. 1987 Mar;19(3):100-3.

PMID:3566031
Abstract

In a previous work on a group of patients with diabetic retinopathy, the effect of laser photocoagulation on the serum zinc and copper levels was evaluated. In many of those patients, an increase in the serum zinc and copper levels was found one day after the laser treatment. In the present work, changes in the serum concentration of these metals after xenon arc photocoagulation were assessed in the rabbit. A significant rise was found one day after the treatment in the level of serum copper (P less than .005), and one week thereafter in the level of serum zinc (P less than .005). The significance of these results and their connection to the retinal pigment epithelium and choroid is discussed.

摘要

在先前一项针对一组糖尿病性视网膜病变患者的研究中,评估了激光光凝对血清锌和铜水平的影响。在许多此类患者中,激光治疗一天后血清锌和铜水平有所升高。在本研究中,评估了氙弧光凝后家兔血清中这些金属浓度的变化。治疗一天后血清铜水平显著升高(P<0.005),一周后血清锌水平显著升高(P<0.005)。讨论了这些结果的意义及其与视网膜色素上皮和脉络膜的关系。

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