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手术创伤引起的血清锌和铜变化以及围手术期和术后补锌的影响。

Changes in serum zinc and copper induced by operative trauma and effects of per- and postoperative zinc infusion.

作者信息

Hallböök T, Hedelin H

出版信息

Acta Chir Scand. 1978;144(7-8):423-6.

PMID:747061
Abstract

Serum zinc, albumin and copper levels were monitored for 5 days after operative trauma in 22 patients. As in earlier studies, a decrease in serum zinc and albumin levels was found. The mean fall in serum zinc was 40% and in albumin, 20%, of the preoperative values. Serum zinc increased after postoperative day 2; albumin remained decreased, indicating a rise in filtrable zinc. A correlation between the fall in serum albumin and serum zinc was found in individual patients. In contrast to previous studies, we found a decrease in serum copper postoperatively. A further 23 patients were supplemented with a zinc and copper containing infusion per- and postoperatively. These patients showed a marked (significant) reduction in the serum zinc fall, the serum level being normalized after 5 days. An insignificant reduction in the fall of serum albumin was also found.

摘要

对22例患者术后创伤后的血清锌、白蛋白和铜水平进行了5天的监测。与早期研究一样,发现血清锌和白蛋白水平下降。血清锌的平均下降幅度为术前值的40%,白蛋白为20%。术后第2天血清锌升高;白蛋白仍降低,表明可滤过锌增加。在个体患者中发现血清白蛋白下降与血清锌之间存在相关性。与之前的研究相反,我们发现术后血清铜下降。另外23例患者在术前和术后补充了含锌和铜的输注液。这些患者的血清锌下降明显(显著)减少,5天后血清水平恢复正常。血清白蛋白下降也有不显著的减少。

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