Silverstone B Z, Landau L, Berson D, Sternbuch J
Ann Ophthalmol. 1985 Jul;17(7):419-22.
Abnormal zinc and copper metabolism has been described in some retinal disorders affecting the retinal pigment epithelium. Anatomic and functional studies in patients with senile macular degeneration show changes in this retinal layer. We examined the blood and urine of two groups of patients, one consisting of patients with senile macular degeneration and the other a control group, for zinc and copper in serum and urine. In the former group we found elevated values of serum zinc and serum copper that were highly significant when compared with the control group. The significance of these findings and their connection to the retinal pigment epithelium is discussed.
在一些影响视网膜色素上皮的视网膜疾病中，已发现锌和铜代谢异常。对老年性黄斑变性患者的解剖学和功能研究表明，该视网膜层存在变化。我们检测了两组患者的血液和尿液，一组为老年性黄斑变性患者，另一组为对照组，检测血清和尿液中的锌和铜含量。在前一组中，我们发现血清锌和血清铜值升高，与对照组相比具有高度显著性。本文讨论了这些发现的意义及其与视网膜色素上皮的关系。
