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右心衰竭:急诊临床医生的叙述性综述。

Right heart failure: A narrative review for emergency clinicians.

机构信息

Department of Emergency Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Department of Emergency Medicine, UT Southwestern, Dallas, TX, USA.

出版信息

Am J Emerg Med. 2022 Aug;58:106-113. doi: 10.1016/j.ajem.2022.05.030. Epub 2022 May 25.

Abstract

INTRODUCTION

Right heart failure (RHF) is a clinical syndrome with impaired right ventricular cardiac output due to a variety of etiologies including ischemia, elevated pulmonary arterial pressure, or volume overload. Emergency department (ED) patients with an acute RHF exacerbation can be diagnostically and therapeutically challenging to manage.

OBJECTIVE

This narrative review describes the pathophysiology of right ventricular dysfunction and pulmonary hypertension, the methods to diagnose RHF in the ED, and management strategies.

DISCUSSION

Right ventricular contraction normally occurs against a low pressure, highly compliant pulmonary vascular system. This physiology makes the right ventricle susceptible to acute changes in afterload, which can lead to RHF. Patients with acute RHF may present with an acute illness and have underlying chronic pulmonary hypertension due to left ventricular failure, pulmonary arterial hypertension, chronic lung conditions, thromboemboli, or idiopathic conditions. Patients can present with a variety of symptoms resulting from systemic edema and hemodynamic compromise. Evaluation with electrocardiogram, laboratory analysis, and imaging is necessary to evaluate cardiac function and end organ injury. Management focuses on treating the underlying condition, optimizing oxygenation and ventilation, treating arrhythmias, and understanding the patient's hemodynamics with bedside ultrasound. As RHF patients are preload dependent they may require fluid resuscitation or diuresis. Hypotension should be rapidly addressed with vasopressors. Cardiac contractility can be augmented with inotropes. Efforts should be made to support oxygenation while trying to avoid intubation if possible.

CONCLUSIONS

Emergency clinician understanding of this condition is important to diagnose and treat this life-threatening cardiopulmonary disorder.

摘要

简介

右心衰竭(RHF)是一种临床综合征,由于多种病因导致右心室心输出量受损,包括缺血、肺动脉压升高或容量超负荷。急诊科(ED)中急性 RHF 加重的患者在诊断和治疗上具有挑战性。

目的

本综述描述了右心室功能障碍和肺动脉高压的病理生理学,ED 中 RHF 的诊断方法以及管理策略。

讨论

右心室收缩通常在低压、高顺应性的肺血管系统中进行。这种生理学使右心室容易受到后负荷的急性变化的影响,从而导致 RHF。急性 RHF 患者可能因急性疾病就诊,且由于左心衰竭、肺动脉高压、慢性肺部疾病、血栓栓塞或特发性疾病而存在潜在的慢性肺动脉高压。患者可能出现多种症状,这些症状源自全身水肿和血流动力学受损。需要进行心电图、实验室分析和影像学评估,以评估心功能和终末器官损伤。管理重点是治疗基础疾病、优化氧合和通气、治疗心律失常以及通过床旁超声了解患者的血流动力学。由于 RHF 患者依赖于前负荷,他们可能需要液体复苏或利尿。应迅速用血管加压素治疗低血压。可以使用正性肌力药增强心肌收缩力。应努力支持氧合,同时尽可能避免插管。

结论

急诊临床医生对这种情况的理解对于诊断和治疗这种危及生命的心肺疾病很重要。

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