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恶性淋巴瘤以下肢作为首发部位。

The lower limb as a presenting site of malignant lymphoma.

作者信息

Stringer M D, Melcher D, Stachan C J

出版信息

Ann R Coll Surg Engl. 1987 Jan;69(1):8-11.

PMID:3566124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2498429/
Abstract

Cutaneous malignant lymphomas should be considered in the differential diagnosis of unusual swellings or ulcers presenting on the limbs. Four cases on the lower limb are described. They may appear as nodules, plaques or ulcers and it is recommended that cytology is used to supplement histology in diagnosis. Successful treatment with radiotherapy is possible but the overall prognosis is frequently poor.

摘要

在鉴别诊断肢体出现的异常肿胀或溃疡时,应考虑皮肤恶性淋巴瘤。本文描述了4例下肢病例。它们可能表现为结节、斑块或溃疡,建议在诊断中使用细胞学检查来辅助组织学检查。放射治疗有可能取得成功,但总体预后往往较差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/2498429/bc934f386eeb/annrcse01542-0015-g.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/2498429/8b8e762d4c55/annrcse01542-0015-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/2498429/f845056a1666/annrcse01542-0015-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/2498429/b8c0bd2f4860/annrcse01542-0015-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/2498429/32bcc113661f/annrcse01542-0015-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/2498429/55749c8aa9f3/annrcse01542-0015-e.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/2498429/3f174ac000a1/annrcse01542-0015-f.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/2498429/bc934f386eeb/annrcse01542-0015-g.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/2498429/8b8e762d4c55/annrcse01542-0015-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/2498429/f845056a1666/annrcse01542-0015-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/2498429/b8c0bd2f4860/annrcse01542-0015-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/2498429/32bcc113661f/annrcse01542-0015-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/2498429/55749c8aa9f3/annrcse01542-0015-e.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/2498429/3f174ac000a1/annrcse01542-0015-f.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/2498429/bc934f386eeb/annrcse01542-0015-g.jpg

相似文献

1
The lower limb as a presenting site of malignant lymphoma.恶性淋巴瘤以下肢作为首发部位。
Ann R Coll Surg Engl. 1987 Jan;69(1):8-11.
2
[Radiotherapy of cutaneous lymphomas excluding mycosis fungoides].[除蕈样肉芽肿外的皮肤淋巴瘤的放射治疗]
Bull Cancer Radiother. 1994;81(3):231-3.
3
Cutaneous malignant lymphoma: a clinical and pathological study of 13 cases.皮肤恶性淋巴瘤:13例临床与病理研究
Eur J Surg Oncol. 1985 Dec;11(4):337-41.
4
Primary malignant lymphoma cutis.原发性皮肤恶性淋巴瘤
Can Med Assoc J. 1977 Oct 8;117(7):750-3.
5
Acute onset of leg nodules in a sporotrichoid pattern--quiz case. Diagnosis: primary cutaneous diffuse large B-cell lymphoma, leg type (PCLBCL-LT).呈孢子丝菌病样模式的腿部结节急性起病——病例分析。诊断:原发性皮肤弥漫性大B细胞淋巴瘤,腿部型(PCLBCL-LT)。
Arch Dermatol. 2012 Oct;148(10):1199-200. doi: 10.1001/archderm.148.10.1199-b.
6
[Primary cutaneous monomelic B-cell lymphoma].[原发性皮肤单肢B细胞淋巴瘤]
Ann Dermatol Venereol. 1997;124(9):633-5.
7
Breast cancer or cutaneous lymphoma?乳腺癌还是皮肤淋巴瘤?
Haematologica. 2000 Oct;85(10):1096.
8
Angiocentric T cell lymphoma of the skin presenting as inflammatory nodules of the leg.
Clin Exp Dermatol. 1997 Mar;22(2):104-8.
9
The histomorphologic spectrum of primary cutaneous diffuse large B-cell lymphoma: a study of 79 cases.原发性皮肤弥漫性大B细胞淋巴瘤的组织形态学谱:79例病例研究
Am J Dermatopathol. 2011 Oct;33(7):649-55; quiz 656-8. doi: 10.1097/DAD.0b013e3181eeb433.
10
Results of radiotherapy in 153 primary cutaneous B-Cell lymphomas classified according to the WHO-EORTC classification.根据世界卫生组织-欧洲肿瘤研究与治疗组织(WHO-EORTC)分类法分类的153例原发性皮肤B细胞淋巴瘤的放疗结果。
Arch Dermatol. 2007 Dec;143(12):1520-6. doi: 10.1001/archderm.143.12.1520.

本文引用的文献

1
Lymphosarcoma: a review of 1269 cases.淋巴肉瘤:1269例病例回顾
Medicine (Baltimore). 1961 Feb;40:31-84. doi: 10.1097/00005792-196102000-00002.
2
An idiopathic leg ulcer as the presenting sign of lymphoma.特发性腿部溃疡作为淋巴瘤的首发症状。
Cutis. 1981 Jul;28(1):43-4.
3
Mycosis fungoides: an overview.蕈样肉芽肿概述
J Surg Oncol. 1983 Apr;22(4):221-7. doi: 10.1002/jso.2930220403.
4
Leg ulcers that do not heal.不愈合的腿部溃疡。
Br Med J (Clin Res Ed). 1983 Jan 15;286(6360):207-8. doi: 10.1136/bmj.286.6360.207.
5
Monoclonal antibody to cytokeratin for use in routine histopathology.用于常规组织病理学的细胞角蛋白单克隆抗体。
J Clin Pathol. 1984 Sep;37(9):975-83. doi: 10.1136/jcp.37.9.975.
6
Primary lymphosarcoma and reticulum cell sarcoma of skin. A review of thirty-two cases.原发性皮肤淋巴肉瘤和网状细胞肉瘤。32例病例回顾。
Clin Radiol. 1972 Jul;23(3):279-85. doi: 10.1016/s0009-9260(72)80046-1.
7
Cutaneous malignant lymphoma: a clinical and pathological study of 13 cases.皮肤恶性淋巴瘤:13例临床与病理研究
Eur J Surg Oncol. 1985 Dec;11(4):337-41.
8
Malignant lymphoma of the skin: a clinicopathologic study of lymphoma other than mycosis fungoides.皮肤恶性淋巴瘤:除蕈样霉菌病之外的淋巴瘤的临床病理研究
Cancer. 1976 Sep;38(3):1282-96. doi: 10.1002/1097-0142(197609)38:3<1282::aid-cncr2820380331>3.0.co;2-n.
9
Cutaneous malignant lymphoma: skin ulcer of lower leg.皮肤恶性淋巴瘤:小腿皮肤溃疡
N Y State J Med. 1979 Aug;79(9):1414-6.