Zhang Xueqian, Su Changyu, Cao Cui, Gong Guiping, Huang Linjuan, Wang Zhongfu, Song Shuang, Zhu Beiwei
College of Food Science and Technology, Northwest University, Xi'an, China.
National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian, China.
Front Nutr. 2022 May 18;9:881464. doi: 10.3389/fnut.2022.881464. eCollection 2022.
is rich in alginate (Alg) and galactofucan (GF) which have both been reported to regulate gut microbiota composition. To reveal the effect of on human gut microbiota, the fecal microbiota of 12 volunteers before and after 14-day intake was sequenced and compared, and the capabilities of the gut microbiota to utilize Alg and GF were also investigated. The 16S rRNA gene sequencing results demonstrated that ratio could be balanced by supplementation. The ability of gut microbiota to utilize Alg was significantly enhanced by supplementation. Furthermore, the multiple linear regression analysis suggested that bacteria from and were positively correlated with Alg utilization while those from , and participated in GF degradation. Moreover, the production of acetic acid and the total short-chain fatty acids (SCFAs) in fermentation were consistent with the consumption of Alg or GF, and propionic acid content was positively correlated with Alg consumption. In addition, the percentage of monosaccharides in the consumed GF after the fermentation suggested that gut microbiota from individuals could consume GF with different monosaccharide preferences. These findings shed a light on the impacts of dietary on human health.
富含藻酸盐（Alg）和岩藻半乳聚糖（GF），据报道这两种物质都能调节肠道微生物群的组成。为了揭示[具体物质]对人体肠道微生物群的影响，对12名志愿者在摄入[具体物质]14天前后的粪便微生物群进行了测序和比较，并研究了肠道微生物群利用Alg和GF的能力。16S rRNA基因测序结果表明，补充[具体物质]可以平衡[具体比例]。补充[具体物质]显著增强了肠道微生物群利用Alg的能力。此外，多元线性回归分析表明，来自[具体菌群]的细菌与Alg利用呈正相关，而来自[具体菌群]的细菌参与了GF的降解。而且，发酵过程中乙酸和总短链脂肪酸（SCFAs）的产生与Alg或GF的消耗一致，丙酸含量与Alg消耗呈正相关。此外，发酵后消耗的GF中单体糖的百分比表明，个体的肠道微生物群可以以不同的单体糖偏好消耗GF。这些发现揭示了饮食[具体物质]对人类健康的影响。
