Goutnik Michael, Lucke-Wold Brandon
Department of Neurosurgery, University of Florida, Gainesville, FL 32608, United States.
World J Clin Oncol. 2022 May 24;13(5):412-416. doi: 10.5306/wjco.v13.i5.412.
Systemic inflammation within malignant glioma is a topic of ongoing significance. In this commentary, we highlight recent findings from Gandhi and discuss alternative approaches. We present a counter argument with findings that IL-6 markers are controversial. We highlight the potential benefit of looking at microRNAs and other biomarkers. Finally, we present ideas for future application involving differentiation between radiation necrosis and recurrence. The commentary is intended to serve as a catalyst for further scientific discovery.
恶性胶质瘤中的全身炎症是一个具有持续重要性的话题。在这篇评论中，我们强调了甘地的近期研究发现并讨论了替代方法。我们提出了一个反对观点，即白细胞介素-6标志物存在争议。我们强调了研究微小RNA和其他生物标志物的潜在益处。最后，我们提出了未来应用的想法，涉及放射性坏死和复发的鉴别。这篇评论旨在成为进一步科学发现的催化剂。
