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甲状腺乳头状癌17年后出现延迟性脑转移且无局部复发:病例报告及文献综述

Delayed brain metastasis after 17-years from papillary thyroid cancer without local recurrence: case report and literature review.

作者信息

Knight James, Kingham Matthew, Price Sally-Ann, Bodi Istvan, Lavrador Jose Pedro

机构信息

Department of Neurosurgery, King's College Hospital, London, SE5 9RS, UK.

GKT School of Medical Education, King's College London, London, SE1 1UL, UK.

出版信息

J Surg Case Rep. 2022 May 31;2022(5):rjac215. doi: 10.1093/jscr/rjac215. eCollection 2022 May.

DOI:10.1093/jscr/rjac215
PMID:35665405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9156030/
Abstract

Papillary thyroid carcinoma (PTC) is the most common malignancy originating from the thyroid, with a good overall prognosis. However, distant metastasis of such lesions is very rare, with the brain being an incredibly uncommon site for secondary spread. The authors report a case of PTC brain metastasis 17-years after successful treatment of the primary malignancy, with no local or locoregional recurrence. Initial diagnostic uncertainty necessitated the involvement of a multidisciplinary team, and eventually the patient underwent image-guided gross surgical resection with intraoperative neuromonitoring (IOMN).

摘要

甲状腺乳头状癌(PTC)是最常见的起源于甲状腺的恶性肿瘤,总体预后良好。然而,此类病变的远处转移非常罕见,脑是极其罕见的继发性扩散部位。作者报告了1例原发性恶性肿瘤成功治疗17年后发生PTC脑转移的病例,无局部或区域复发。最初的诊断不确定性需要多学科团队参与,最终患者接受了术中神经监测(IOMN)下的影像引导大体手术切除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/623b/9156030/bc3d2ad2d944/rjac215f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/623b/9156030/6b36bc31dcb0/rjac215f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/623b/9156030/bc3d2ad2d944/rjac215f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/623b/9156030/6b36bc31dcb0/rjac215f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/623b/9156030/bc3d2ad2d944/rjac215f2.jpg

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本文引用的文献

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BMJ Case Rep. 2016 Mar 9;2016:bcr2015213824. doi: 10.1136/bcr-2015-213824.
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Features Predictive of Distant Metastasis in Papillary Thyroid Microcarcinomas.甲状腺微小乳头状癌远处转移的预测因素。
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