From the Department of Plastic Surgery, University of Pittsburgh Medical Center.
Plast Reconstr Surg. 2022 Aug 1;150(2):329e-336e. doi: 10.1097/PRS.0000000000009355. Epub 2022 Jun 6.
Fat grafting is one of the most revolutionary surgical techniques of our century, and it has changed the field of plastic surgery and regenerative medicine. Early reports of fat grafting date back to the late nineteenth century, but the results were unsatisfactory because of minimal graft retention. It was not until Sydney R. Coleman challenged the dogma and introduced a standardized approach to fat grafting after years of research and learning from experts across the world. The Coleman technique represents an evolutionary approach to fat grafting, with three main components: harvesting, refinement, and placement. The Coleman technique has been adopted and modified by surgeons around the world because it has allowed a reliable increase in fat graft survival through a standardized process. This article discusses the influencing factors and milestones that led to this world-known technique, in addition to Dr. Coleman's current practices, pearls, pitfalls, and lessons learned over the years. The knowledge of the true potential and usefulness of fat is in its infancy, with its regenerative potential becoming increasingly recognized. Current and future research will likely prove that autologous fat has many clinical applications beyond its well-known aesthetic and reconstructive benefits and extending beyond the regenerative realm.
脂肪移植是我们这个世纪最具革命性的外科技术之一，它改变了整形外科学和再生医学领域。脂肪移植的早期报道可以追溯到 19 世纪末，但由于移植物保留率低，效果并不理想。直到悉尼·R·科尔曼（Sydney R. Coleman）经过多年的研究并向世界各地的专家学习后，挑战了这一教条，并提出了一种标准化的脂肪移植方法，情况才有所改变。科尔曼技术代表了脂肪移植的一种演进方法，主要有三个组成部分：采集、细化和放置。科尔曼技术已被世界各地的外科医生采用和修改，因为它通过标准化的流程实现了脂肪移植存活率的可靠提高。本文讨论了促成这一闻名世界的技术的影响因素和里程碑事件，以及科尔曼博士目前的实践、经验、教训和多年来的心得。对脂肪真正潜力和用途的认识还处于起步阶段，其再生潜力正逐渐得到认可。目前和未来的研究可能会证明，自体脂肪除了众所周知的美容和重建益处之外，还有许多临床应用，其应用范围不仅限于再生领域。
