反复短时间缺氧暴露对自发性高血压大鼠和WKY大鼠血压发展及红细胞钠含量的长期影响。
Long-term effect of repeated short oxygen exposition on blood pressure development and erythrocyte sodium content in SHR and WKY.
作者信息
Gross V, Moritz V, Gnüchtel U, Flemming B, Roloff D, Oddoy A
出版信息
Biomed Biochim Acta. 1986;45(10):K47-52.
PMID:3566715
Abstract
Repeated short oxygen exposition (60 min weekly, beginning at the 1st week of age up to the 18th week of age) induced in male spontaneously hypertensive rats (SHR) a diminished blood pressure rise. Oxygen exposed SHR had also lower heart rates than SHR without oxygen exposition. No significant differences were found in both these parameters in normotensive rats (WKY). Furthermore oxygen exposition decreased the erythrocyte sodium content of SHR.
摘要
对雄性自发性高血压大鼠（SHR）进行反复短期缺氧暴露（每周60分钟，从出生第1周开始直至第18周龄），可导致其血压升高幅度减小。缺氧暴露的SHR心率也低于未进行缺氧暴露的SHR。在正常血压大鼠（WKY）中，这两个参数均未发现显著差异。此外，缺氧暴露降低了SHR的红细胞钠含量。
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