Faculty of Medicine, Imperial College London, London, UK.
Stroke, London North West University Healthcare NHS Trust, Harrow, Middlesex, UK
BMJ Case Rep. 2022 Jun 6;15(6):e247234. doi: 10.1136/bcr-2021-247234.
A woman in her 50s presented with acute vertigo and vomiting within 72 hours of receiving the Pfizer-BioNTech COVID-19 vaccine. The only neurological deficit was an impaired vestibulo-ocular reflex with horizontal nystagmus. The patient was subsequently diagnosed with vestibular neuronitis. She was managed symptomatically with prochlorperazine and betahistine, and underwent vestibular rehabilitation for 6 weeks. She made a full recovery and experienced no further symptoms. She received the second dose of the vaccine without complications.This case demonstrates a temporal association between COVID-19 vaccination and vestibular neuronitis. Neurological adverse events are rare but recognised side effects of COVID-19 vaccines and healthcare professionals should be aware of them. This ensures timely management of patients with such presentations. Treatment should be the same as for non-vaccine-associated vestibular neuronitis. The nature of the relationship between COVID-19 vaccination and vestibular neuronitis remains unclear and patients therefore require investigations to exclude other recognised causes of vestibular neuronitis.
一位 50 多岁的女性在接种辉瑞-生物科技公司的 COVID-19 疫苗后 72 小时内出现急性眩晕和呕吐。唯一的神经系统缺损是前庭眼反射受损伴水平眼球震颤。随后诊断为前庭神经元炎。她接受了异丙嗪和倍他司汀对症治疗，并进行了 6 周的前庭康复治疗。她完全康复，没有出现进一步的症状。她没有出现并发症就接种了第二剂疫苗。本病例表明 COVID-19 疫苗接种与前庭神经元炎之间存在时间关联。神经系统不良反应罕见，但却是 COVID-19 疫苗的已知副作用，医护人员应了解这些副作用。这可确保及时对有此类表现的患者进行管理。治疗方法与非疫苗相关的前庭神经元炎相同。COVID-19 疫苗接种与前庭神经元炎之间的关系性质尚不清楚，因此患者需要进行检查以排除其他公认的前庭神经元炎病因。
