早发型糖尿病患者的糖尿病视网膜病变和糖尿病性黄斑水肿
Diabetic Retinopathy and Diabetic Macular Edema in People With Early-Onset Diabetes.
作者信息
Reddy Nikitha Gurram, Venkatesh Ramesh, Jayadev Chaitra, Gadde Santosh Gopi Krishna, Agrawal Sameeksha, Mishra Pranjal, Yadav Naresh Kumar, Chhablani Jay
机构信息
Department of Retina and Vitreous, Narayana Nethralaya, Bangalore, India.
Medical Retina and Vitreoretinal Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA.
出版信息
Clin Diabetes. 2022 Spring;40(2):222-232. doi: 10.2337/cd21-0110. Epub 2022 Apr 15.
Abstract
This study examined the clinical profile, treatment profile, and vision outcomes of people ≤40 years of age with diabetes and diabetic macular edema (DME). Within this age-group, the prevalence of center-involving DME was 16%, with 74% of eyes showing cystoid edema, 37% showing spongiform edema, and 41% having neurosensory detachment. Longer diabetes duration ( = 0.001) and greater severity of diabetic retinopathy ( <0.001) were associated with DME prevalence. Thus, regular and more frequent follow-up, as well as early and aggressive treatment of diabetic eye disease, are required in people diagnosed early with diabetes.
摘要
本研究调查了年龄≤40岁的糖尿病及糖尿病性黄斑水肿（DME）患者的临床特征、治疗情况及视力预后。在该年龄组中，累及黄斑中心凹的DME患病率为16%，74%的患眼表现为囊样水肿，37%表现为海绵状水肿，41%存在神经感觉层脱离。糖尿病病程较长（P = 0.001）及糖尿病视网膜病变程度较重（P <0.001）与DME患病率相关。因此，对于早期诊断为糖尿病的患者，需要进行定期且更频繁的随访，以及对糖尿病眼病进行早期积极治疗。
相似文献
1
Diabetic Retinopathy and Diabetic Macular Edema in People With Early-Onset Diabetes.早发型糖尿病患者的糖尿病视网膜病变和糖尿病性黄斑水肿
Clin Diabetes. 2022 Spring;40(2):222-232. doi: 10.2337/cd21-0110. Epub 2022 Apr 15.
2
Spectral domain optical coherence tomography classification of diabetic macular edema: a new proposal to clinical practice.谱域光学相干断层扫描对糖尿病性黄斑水肿的分类：对临床实践的新建议。
Graefes Arch Clin Exp Ophthalmol. 2020 Jun;258(6):1165-1172. doi: 10.1007/s00417-020-04640-9. Epub 2020 Mar 9.
3
[Evaluate the effectiveness of laser therapy in the treatment of diabetic maculopathy].评估激光治疗糖尿病性黄斑病变的有效性。
Pol Merkur Lekarski. 2013 Jun;34(204):351-4.
4
Is immediate treatment necessary for diabetic macular edema after pars plana vitrectomy for tractional complications of proliferative diabetic retinopathy?对于增殖性糖尿病视网膜病变牵引性并发症行玻璃体切割术后的糖尿病性黄斑水肿，是否需要立即进行治疗？
Int Ophthalmol. 2021 Nov;41(11):3607-3614. doi: 10.1007/s10792-021-01923-w. Epub 2021 Jun 25.
5
Optical coherence tomography for the detection of early macular edema in diabetic patients with retinopathy.光学相干断层扫描用于检测糖尿病视网膜病变患者的早期黄斑水肿。
Folia Med (Plovdiv). 2010 Jan-Mar;52(1):40-8.
6
Visual outcomes of observation, macular laser and anti-VEGF in diabetic macular edema in type 1 diabetes: a real-world study.1 型糖尿病患者糖尿病性黄斑水肿中观察、黄斑激光和抗 VEGF 治疗的视力结果：一项真实世界研究。
BMC Ophthalmol. 2022 Jun 9;22(1):258. doi: 10.1186/s12886-022-02482-z.
7
Prevalence of and Risk Factors for Diabetic Retinopathy and Diabetic Macular Edema in Patients with Early- and Late-Onset Diabetes Mellitus.早发和晚发糖尿病患者糖尿病视网膜病变和糖尿病黄斑水肿的患病率及其危险因素。
Ophthalmic Res. 2022;65(3):293-299. doi: 10.1159/000508335. Epub 2020 Apr 30.
8
The use of micropulse laser in patients with diabetic macular edema at the Department of Ophthalmology, Faculty Hospital Hradec Králové.克拉德诺市大学医院眼科对糖尿病性黄斑水肿患者使用微脉冲激光治疗。
Cesk Slov Oftalmol. 2018 Summer;74(2):53-58. doi: 10.31348/2018/1/2-2-2018.
9
Changes in choroidal thickness in relation to the severity of retinopathy and macular edema in type 2 diabetic patients.2 型糖尿病患者视网膜病变和黄斑水肿严重程度与脉络膜厚度变化的关系。
Invest Ophthalmol Vis Sci. 2013 May 9;54(5):3378-84. doi: 10.1167/iovs.12-11503.
10
[Epidemiology of diabetic macular edema in patients with type 2 diabetes in the Beixinjing District of Shanghai].[上海市北新泾地区2型糖尿病患者糖尿病性黄斑水肿的流行病学研究]
Zhonghua Yan Ke Za Zhi. 2007 Jul;43(7):626-30.
引用本文的文献
1
Hybrid Explainable Artificial Intelligence Models for Targeted Metabolomics Analysis of Diabetic Retinopathy.用于糖尿病视网膜病变靶向代谢组学分析的混合可解释人工智能模型
Diagnostics (Basel). 2024 Jun 27;14(13):1364. doi: 10.3390/diagnostics14131364.
2
Preservation of Intrinsically Photosensitive Retinal Ganglion Cells (ipRGCs) in Late Adult Mice: Implications as a Potential Biomarker for Early Onset Ocular Degenerative Diseases.成年晚期小鼠内源性感光视网膜神经节细胞（ipRGCs）的保存：作为早期发作的眼部退行性疾病的潜在生物标志物的意义。
Invest Ophthalmol Vis Sci. 2024 Jan 2;65(1):28. doi: 10.1167/iovs.65.1.28.
本文引用的文献
1
Intracystic hyperreflective material in centre-involving diabetic macular oedema.中心性糖尿病黄斑水肿中囊内高反射物质。
Graefes Arch Clin Exp Ophthalmol. 2021 Sep;259(9):2533-2544. doi: 10.1007/s00417-021-05083-6. Epub 2021 Mar 12.
2
Impact of treatment of diabetic macular edema on visual impairment in people with diabetes mellitus in India.印度糖尿病患者糖尿病性黄斑水肿治疗对视力损害的影响。
Indian J Ophthalmol. 2021 Mar;69(3):671-676. doi: 10.4103/ijo.IJO_2614_20.
3
Prevalence of and Risk Factors for Diabetic Retinopathy and Diabetic Macular Edema in Patients with Early- and Late-Onset Diabetes Mellitus.早发和晚发糖尿病患者糖尿病视网膜病变和糖尿病黄斑水肿的患病率及其危险因素。
Ophthalmic Res. 2022;65(3):293-299. doi: 10.1159/000508335. Epub 2020 Apr 30.
4
Hyperreflective Foci in the Outer Retinal Layers as a Predictor of the Functional Efficacy of Ranibizumab for Diabetic Macular Edema.外视网膜层的高反射焦点可预测雷珠单抗治疗糖尿病性黄斑水肿的功能疗效。
Sci Rep. 2020 Jan 21;10(1):873. doi: 10.1038/s41598-020-57646-y.
5
Classifications of diabetic macular edema.糖尿病性黄斑水肿的分类
Eur J Ophthalmol. 2020 Jan;30(1):6-7. doi: 10.1177/1120672119889532. Epub 2019 Nov 26.
6
The Diabetic Retinopathy Clinical Research Network (DRCR.net) and Its Contributions to the Treatment of Diabetic Retinopathy.糖尿病视网膜病变临床研究网络（DRCR.net）及其对糖尿病视网膜病变治疗的贡献。
Ophthalmic Res. 2019;62(4):225-230. doi: 10.1159/000502779. Epub 2019 Sep 25.
7
Hyperreflective foci in OCT image as a biomarker of poor prognosis in diabetic macular edema patients treating with Conbercept in China.在中国，光学相干断层扫描（OCT）图像中的高反射灶作为糖尿病性黄斑水肿患者接受康柏西普治疗预后不良的生物标志物。
BMC Ophthalmol. 2019 Jul 23;19(1):157. doi: 10.1186/s12886-019-1168-0.
8
Effect of Initial Management With Aflibercept vs Laser Photocoagulation vs Observation on Vision Loss Among Patients With Diabetic Macular Edema Involving the Center of the Macula and Good Visual Acuity: A Randomized Clinical Trial.阿柏西普与激光光凝及观察治疗对中心性浆液性脉络膜视网膜病变黄斑区累及及良好视力患者视力丧失影响的随机临床试验
JAMA. 2019 May 21;321(19):1880-1894. doi: 10.1001/jama.2019.5790.
9
Evaluation of markers of outcome in real-world treatment of diabetic macular edema.糖尿病性黄斑水肿实际治疗中预后指标的评估
Eye Vis (Lond). 2018 Oct 11;5:27. doi: 10.1186/s40662-018-0119-9. eCollection 2018.
10
Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema: recent clinically relevant findings from DRCR.net Protocol T.阿柏西普、贝伐单抗或雷珠单抗治疗糖尿病性黄斑水肿：DRCR.net方案T的近期临床相关研究结果
Curr Opin Ophthalmol. 2017 Nov;28(6):636-643. doi: 10.1097/ICU.0000000000000424.
Zotero 插件