Department of Pharmacy, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Key Laboratory of Assessment of Clinical Drugs Risk and Individual Application (Beijing Hospital), Beijing 100730, China.
Department of Pharmacy, China Aerospace Science & Industry Corporation 731 Hospital, Beijing 100000, China.
Comput Math Methods Med. 2022 May 28;2022:5197871. doi: 10.1155/2022/5197871. eCollection 2022.
This research was aimed at discussing the application value of coagulation function detection and three-dimensional echocardiography in the prognosis evaluation of acute myocardial infarction (AMI) patients. 72 patients with AMI were divided into the recovered group (good recovery) and unrecovered group (poor recovery) according to the results of postoperative ultrasonography. The left ventricular parameters of the patients were detected by three-dimensional ultrasound, and the coagulation function was also detected. The results showed that 3 months after surgery, the regional end-systolic volume (rESV) and regional end-diastolic volume (rEDV) of the left ventricle in the patients were smaller than the measured values 1 week after surgery. The left ventricular regional ejection fraction (rEF) was greater than the value measured 1 week after surgery, and all the differences were statistically significant ( < 0.05). For the end-systolic volume (ESV), end-diastolic volume (EDV), and ejection fraction (EF) (%), the two-dimensional ultrasound results were significantly lower than the three-dimensional ultrasound results, and there were significant differences ( < 0.05). Tmsvle6-Dif% of the recovered patients was 14.99 ± 9.88 and 14.37 ± 9.78 3 months and 6 months after surgery, respectively. These were smaller than 30.91 ± 18.63 and 33.51 ± 17.96 of the unrecovered patients; the differences were of statistical significance ( < 0.05). Tmsvl6-SD% of recovered patients was 3.69 ± 2.47 and 3.61 ± 1.83 3 months and 6 months after surgery, respectively, which were also smaller than 7.38 ± 4.06 and 7.96 ± 2.82 of unrecovered patients, showing statistically significant difference ( < 0.05). The postoperative Tmsvle6-Dif% and Tmsvl6-SD% of the recovered group were lower than those of the unrecovered patients, with the statistically significant differences ( < 0.05). The level of coagulation factors in the recovered group was also significantly lower than that in the unrecovered group with the difference statistically significant ( < 0.05). The results suggested that three-dimensional echocardiography played an important role in the evaluation of cardiac conditions in AMI patients. The level of coagulation factors varied with the AMI condition of patients, and there was an obvious relationship between them, which could provide a reference value for the prognosis evaluation of patients.
本研究旨在探讨凝血功能检测和三维超声心动图在急性心肌梗死(AMI)患者预后评估中的应用价值。根据术后超声检查结果,将 72 例 AMI 患者分为恢复组(恢复良好)和未恢复组(恢复不良)。采用三维超声检测患者左心室参数,并检测凝血功能。结果显示,术后 3 个月,患者左心室局部收缩末期容积(rESV)和局部舒张末期容积(rEDV)均小于术后 1 周测量值,左心室局部射血分数(rEF)大于术后 1 周测量值,差异均有统计学意义(<0.05)。二维超声 ESV、EDV 和 EF(%)结果明显低于三维超声结果,差异有统计学意义(<0.05)。恢复组患者的 Tmsvle6-Dif%术后 3 个月和 6 个月分别为 14.99±9.88 和 14.37±9.78,均小于未恢复组的 30.91±18.63 和 33.51±17.96,差异有统计学意义(<0.05)。恢复组患者的 Tmsvl6-SD%术后 3 个月和 6 个月分别为 3.69±2.47 和 3.61±1.83,也小于未恢复组的 7.38±4.06 和 7.96±2.82,差异有统计学意义(<0.05)。恢复组患者术后 Tmsvle6-Dif%和 Tmsvl6-SD%均低于未恢复组,差异有统计学意义(<0.05)。恢复组凝血因子水平也明显低于未恢复组,差异有统计学意义(<0.05)。结果表明,三维超声心动图在评价 AMI 患者心脏状况方面发挥着重要作用。凝血因子水平随患者 AMI 病情变化而变化,二者之间存在明显关系,可为患者预后评估提供参考价值。