Cavalier Joanna S, Klem Igor
Division of Cardiology, Duke University Medical Center, Durham, NC, USA.
Duke Cardiovascular Magnetic Resonance Center, Duke University Medical Center, Durham, NC, USA.
J Cardiovasc Imaging. 2021 Apr;29(2):91-107. doi: 10.4250/jcvi.2021.0036.
Chest pain is one of the most common presenting symptoms in the emergency department (ED). Among patients with abnormal troponins, it is imperative to quickly and accurately distinguish type 1 acute myocardial infarction (AMI) from other etiologies of myocardial injury. Although high-sensitivity troponin assays introduced a high negative predictive value for AMI, they have exposed the need for diagnostic modalities that can determine the etiology of acute myocardial injury. Cardiac magnetic resonance imaging (CMR) is an effective tool to risk stratifying chest pain among patients in the ED. CMR is non-invasive and has a lower cost of care and shorter length of stay compared to those of invasive coronary angiography. It also provides detailed information on cardiac morphology, function, tissue edema, and location and pattern of tissue damage that can help to differentiate many etiologies of cardiac injury. CMR is particularly useful to distinguish chest pain due to type 1 AMI versus supply-demand mismatch due to acute cardiac noncoronary artery disease. A detailed review of the literature has shown that CMR with stress testing is safe to use in patients presenting to the ED with chest pain, with or without abnormal troponins. CMR is a useful, safe, economical, and effective alternative to the traditional diagnostic tools that are typically used in this patient population. It is a practical tool to risk-stratify patients with possible cardiac pathology and to clarify diagnosis without invasive testing.
胸痛是急诊科最常见的就诊症状之一。在肌钙蛋白异常的患者中,迅速准确地区分1型急性心肌梗死(AMI)与其他心肌损伤病因至关重要。尽管高敏肌钙蛋白检测对AMI具有较高的阴性预测价值,但它们也凸显了对能够确定急性心肌损伤病因的诊断方法的需求。心脏磁共振成像(CMR)是对急诊科患者胸痛进行风险分层的有效工具。与有创冠状动脉造影相比,CMR是非侵入性的,护理成本更低,住院时间更短。它还能提供有关心脏形态、功能、组织水肿以及组织损伤的位置和模式的详细信息,有助于区分多种心脏损伤病因。CMR对于区分1型AMI引起的胸痛与急性非冠状动脉疾病导致的供需不匹配特别有用。对文献的详细回顾表明,无论是肌钙蛋白正常还是异常,CMR负荷试验用于急诊科胸痛患者都是安全的。CMR是该患者群体中常用的传统诊断工具的一种有用、安全、经济且有效的替代方法。它是一种实用工具,可对可能患有心脏疾病的患者进行风险分层,并在无需进行侵入性检查的情况下明确诊断。