Adan Ali Hassan, Farah Yusuf Mohamud Mohamed
Emergency Department, Mogadishu Somali Turkey Training and Research Hospital, Mogadishu, Somalia.
Int J Gen Med. 2022 May 30;15:5297-5306. doi: 10.2147/IJGM.S364202. eCollection 2022.
An altered level of consciousness (ALOC) means that the patient is not as awake, alert, or able to understand or react to the surrounding environment. The main purpose of this study was to investigate the epidemiology, risk factors, and etiology of altered levels of consciousness among patients attending the Emergency Department.
The study was conducted in the Mogadishu-Somali-Turkey Training and Research Hospital in Mogadishu, Somalia, as a prospective observational study. A total of 155 adult patients with a GCS ≤12 were admitted to the emergency room for traumatic and non-traumatic ALOC between March and June 2021.
Our study enrolled 155 (2.6%) of the 6000 patients hospitalized in the emergency room. 60% (n = 93) were males and 40% (n = 62) were females. The mean age of the participants was 46.7 ± 22.4 years. The most common presenting features were dyspnea (21.9%), injuries (20%), hemiplegia (16.8%), convulsion (16.8%), and oliguria (12.3%). 119 (77%) cases had a GCS = 3-8, while 36 (23%) had a GCS = 9-12. Most of the participants with ALOC had a history of hypertension (27.7%, n = 43), 34 (21.9%) had diabetes, 6 (3.9%) had epilepsy, and 4 (2.6%) had chronic renal disease. Cerebro-vascular-accidents (24.5%) were the most common cause of ALOC, followed by organ failure and traumatic brain injury (22% each), infections (12.2%), diabetic emergencies, hypoglycemia (11.6%), shock, and status epilepticus (4% each).
Male sex, older age, hypertension, and diabetes were the main risk factors for our study participants, while uremic encephalopathy, ischemic stroke, hemorrhagic stroke, sepsis syndrome, and subdural hematoma were the most common causes of ALOC.
意识水平改变(ALOC)是指患者不像往常那样清醒、警觉,或者无法理解周围环境或对其做出反应。本研究的主要目的是调查急诊科患者意识水平改变的流行病学、危险因素和病因。
本研究在索马里摩加迪沙的摩加迪沙-索马里-土耳其培训与研究医院进行,是一项前瞻性观察性研究。2021年3月至6月期间,共有155例格拉斯哥昏迷量表(GCS)≤12分的成年患者因创伤性和非创伤性意识水平改变被收治入急诊室。
我们的研究纳入了急诊室6000例住院患者中的155例(2.6%)。60%(n = 93)为男性,40%(n = 62)为女性。参与者的平均年龄为46.7±22.4岁。最常见的临床表现为呼吸困难(21.9%)、损伤(20%)、偏瘫(16.8%)、抽搐(16.8%)和少尿(12.3%)。119例(77%)患者的GCS评分为3 - 8分,36例(23%)患者的GCS评分为9 - 12分。大多数意识水平改变的参与者有高血压病史(27.7%,n = 43),34例(21.9%)患有糖尿病,6例(3.9%)患有癫痫,4例(2.6%)患有慢性肾病。脑血管意外(24.5%)是意识水平改变最常见的原因,其次是器官衰竭和创伤性脑损伤(各占22%)、感染(12.2%)、糖尿病急症、低血糖(11.6%)、休克和癫痫持续状态(各占4%)。
男性、年龄较大、高血压和糖尿病是我们研究参与者的主要危险因素,而尿毒症性脑病缺血性卒中、出血性卒中、脓毒症综合征和硬膜下血肿是意识水平改变最常见的原因。