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有机溶剂与早老性痴呆:一项使用死亡证明的病例对照研究。

Organic solvents and presenile dementia: a case referent study using death certificates.

作者信息

O'Flynn R R, Monkman S M, Waldron H A

出版信息

Br J Ind Med. 1987 Apr;44(4):259-62. doi: 10.1136/oem.44.4.259.

Abstract

Occupational exposure to organic solvents has been implicated in the development of "presenile dementia" in several studies. The death certificates of all men aged under 65 dying in England and Wales bearing presenile dementia as cause of death were collected for the years 1970-9 (n = 557): control death certificates were obtained, matched for age and sex. No significant differences were found between the groups as regards estimated occupational exposure to either organic solvents or lead.

摘要

几项研究表明,职业性接触有机溶剂与“早老性痴呆”的发病有关。收集了1970年至1979年期间在英格兰和威尔士死亡的所有65岁以下男性的死亡证明,这些男性的死因是早老性痴呆(n = 557):并获取了年龄和性别匹配的对照死亡证明。在估计的有机溶剂或铅职业接触方面,两组之间未发现显著差异。

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本文引用的文献

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Occupational solvent exposure and neuropsychiatric disorders.
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Death certification.死亡证明。
Br Med J (Clin Res Ed). 1983 Aug 13;287(6390):444-5. doi: 10.1136/bmj.287.6390.444.
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Death certification from the epidemiological point of view.
Lancet. 1981 Oct 3;2(8249):742-3. doi: 10.1016/s0140-6736(81)91062-x.
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Diagnostic errors discovered at autopsy.尸检时发现的诊断错误。
Acta Med Scand. 1974 Sep;196(3):203-10. doi: 10.1111/j.0954-6820.1974.tb00996.x.
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Outcome of investigation of patients with presenile dementia.早老性痴呆患者的调查结果
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A case-control study of dementia of the Alzheimer type.
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