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[用催产素处理的未孕大鼠和孕鼠子宫浆膜微循环障碍的比较特征]

[Comparative characteristics of microcirculation disorders in the serous membrane of the uterus in intact and pregnant rats treated with oxytocin].

作者信息

Ovsiannikov V G, Fomina I V, Orlov V I

出版信息

Biull Eksp Biol Med. 1987 Apr;103(4):476-8.

PMID:3567346
Abstract

The studies were performed on intact and pregnant rats after the administration of 10(-2) U of oxytocin. Oxytocin-induced increase in spasm duration and microvascular dilatation was noted both in intact and pregnant animals. However, in the former case spasm duration was markedly increased, while in the latter case there was an equal increase both in spasm duration and dilatation. Dilatation phase was characterized by an increase in microvessel diameter, as compared to the initial one. Maximal spasm phase after oxytocin administration in intact rats was characterized by hemostasis. In pregnant animals blood flow was delayed, with no marked spasm present. The initial level of microcirculation was restored 38-40 minutes later.

摘要

在给完整大鼠和怀孕大鼠注射10(-2)单位催产素后进行了这些研究。在完整动物和怀孕动物中均观察到催产素引起的痉挛持续时间增加和微血管扩张。然而,在前一种情况下痉挛持续时间明显增加,而在后一种情况下痉挛持续时间和扩张均有同等程度的增加。与初始状态相比,扩张期的特征是微血管直径增加。完整大鼠注射催产素后的最大痉挛期以止血为特征。在怀孕动物中血流延迟,无明显痉挛。38 - 40分钟后微循环恢复到初始水平。

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