Division of Periodontology and Implant Dentistry Faculty of Dentistry, The University of Hong Kong, Hong Kong, SAR, China.
Dr D. Y. Patil Dental College and Hospital, Dr D. Y. Patil Vidyapeeth, Pune, India.
Int J Implant Dent. 2022 Jun 8;8(1):26. doi: 10.1186/s40729-022-00426-2.
The purpose of this umbrella review was to gather and summarize the data from published systematic reviews (SRs) that compared non-surgical mechanical debridement (NSMD) with and without the use of adjunctive treatments on the management of peri-implant mucositis (PIM).
A protocol was developed and registered in PROSPERO (CRD42021254350) before the systematic search for the SRs. Seven electronic databases, including Cochrane Library, Embase (via Ovid), MEDLINE (via Pubmed), Proquest, Prospero, Scopus and Web of Science, were searched for published reviews. The search for unpublished and informally published reviews was further attempted in the last four databases. The methodological quality of the included reviews was assessed using AMSTAR 2.
Twelve included SRs assessed clinical studies published between 2014 and 2020, including a total of seventeen primary clinical trials. All SRs summarized data from individual studies and provided a narrative conclusion regarding the effectiveness of the adjunctive treatments. Only six SRs performed a meta-analysis (MA) of additional benefits of the adjunctive therapy for PIM, with results indicating no significant difference between the different treatment modalities. The overall confidence was adjudged ranging from critically low to low using AMSTAR 2 and significant additional benefits of any adjunctive treatments in comparison with NSMD were not apparent.
Overall, the reviewed evidence did not support the use of adjunctive treatments for improvement of clinical outcomes in PM management as compared to NSMD alone.
本综述的目的是收集和总结已发表的系统评价（SR）的数据，这些系统评价比较了非手术机械清创（NSMD）与和不与附加治疗联合用于治疗种植体周围黏膜炎（PIM）的效果。
在进行系统检索之前，制定了一份方案并在 PROSPERO（CRD42021254350）中进行了注册。检索了 Cochrane Library、Embase（通过 Ovid）、MEDLINE（通过 Pubmed）、Proquest、Prospero、Scopus 和 Web of Science 这 7 个电子数据库，以查找已发表的综述。进一步在最后 4 个数据库中尝试检索未发表和非正式发表的综述。使用 AMSTAR 2 评估纳入综述的方法学质量。
纳入的 12 项 SR 评估了 2014 年至 2020 年期间发表的临床研究，包括总共 17 项原始临床试验。所有 SR 都总结了来自个别研究的数据，并就附加治疗的有效性提供了叙述性结论。只有 6 项 SR 对附加治疗对 PIM 的额外益处进行了荟萃分析（MA），结果表明不同治疗方式之间无显著差异。使用 AMSTAR 2 评估总体置信度从严重低到低，并且没有明显证据表明任何附加治疗在与 NSMD 相比时具有显著额外益处。
总体而言，与单独使用 NSMD 相比，审查的证据不支持将附加治疗用于改善 PM 管理的临床结局。
