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多氯联苯(PCBs)的暴露源和健康风险评估:伊朗的系统评价。

Exposure sources of polychlorinated biphenyls (PCBs) and health risk assessment: a systematic review in Iran.

机构信息

Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, PourSina St., Qods St., Enghelab St, Tehran, 141761315, Iran.

Department of Environmental Health Engineering, Faculty of Health and Nutrition, Bushehr University of Medical Sciences, Bushehr, Iran.

出版信息

Environ Sci Pollut Res Int. 2022 Aug;29(37):55437-55456. doi: 10.1007/s11356-022-21274-y. Epub 2022 Jun 8.

Abstract

This systematic review aims to identify the sources of exposure to polychlorinated biphenyls (PCBs), portioning, and human health risk assessment in Iran. The literature was searched in the international databases of Web of Science, PubMed, Scopus, Google Scholar, and the national databases of SID and MagIran up to November 14, 2020. Among all 153 articles, 21 eligible papers were identified. Among them, only one article was related to drinking water, the rest was related to food and soil, and no article was found on ambient air. The corrected portion of each exposure source was determined to be 90% for food, 9% for water, and 1% for air. The total hazard quotient (HQ) was determined to be within an unsafe range, and the total excess lifetime cancer risk (ELCR) was determined to be at a high risk of oral carcinogenesis. It is suggested that a comprehensive study be conducted in a specific period for all sources of exposure in all counties of Iran. Moreover, it is recommended that the policymakers set national standards for this pollutant in near future in some sources of exposure (e.g., drinking water) which have no standards in Iran.

摘要

本系统评价旨在确定伊朗多氯联苯(PCBs)的暴露源、分配情况和人类健康风险评估。文献检索范围为 2020 年 11 月 14 日之前国际的 Web of Science、PubMed、Scopus、Google Scholar 和国内的 SID 和 MagIran 数据库。在所有 153 篇文章中,确定了 21 篇符合条件的文章。其中,只有一篇文章与饮用水有关,其余均与食物和土壤有关,未发现与环境空气有关的文章。确定每个暴露源的修正部分分别为:食物 90%、水 9%、空气 1%。总危害商数(HQ)被确定为处于不安全范围,总超额终生癌症风险(ELCR)被确定为具有高致癌风险。因此建议在伊朗所有县的特定时期内对所有暴露源进行综合研究。此外,建议决策者在近期内为伊朗一些没有标准的暴露源(如饮用水)制定此类污染物的国家标准。

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