Department of Gastroenterology, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Hunan Key Laboratory of Nonresolving Inflammation and Cancer, Changsha, Hunan, China.
Front Public Health. 2023 Feb 24;11:1140786. doi: 10.3389/fpubh.2023.1140786. eCollection 2023.
Inflammatory bowel disease (IBD) is becoming increasingly prevalent with the improvement of people's living standards in recent years, especially in urban areas. The emerging environmental contaminant is a newly-proposed concept in the progress of industrialization and modernization, referring to synthetic chemicals that were not noticed or researched before, which may lead to many chronic diseases, including IBD. The emerging contaminants mainly include microplastics, endocrine-disrupting chemicals, chemical herbicides, heavy metals, and persisting organic pollutants. In this review, we summarize the adverse health effect of these emerging contaminants on humans and their relationships with IBD. Therefore, we can better understand the impact of these new emerging contaminants on IBD, minimize their exposures, and lower the future incidence of IBD.
近年来，随着人们生活水平的提高，炎症性肠病（IBD）的发病率也越来越高，尤其是在城市地区。新兴环境污染物是在工业化和现代化进程中提出的新概念，指的是以前未被注意或研究过的合成化学物质，可能导致许多慢性疾病，包括 IBD。新兴污染物主要包括微塑料、内分泌干扰化学物质、化学除草剂、重金属和持久性有机污染物。在这篇综述中，我们总结了这些新兴污染物对人类健康的不良影响及其与 IBD 的关系。因此，我们可以更好地了解这些新出现的污染物对 IBD 的影响，尽量减少它们的暴露，并降低未来 IBD 的发病率。
